Department of Radiology, Charité - University Medicine, Berlin, Germany.
Eur J Radiol. 2011 Mar;77(3):426-35. doi: 10.1016/j.ejrad.2009.08.014. Epub 2009 Sep 23.
We sought to determine the comparability of multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) for measuring the aortic valve orifice area (AVA) and grading aortic valve stenosis.
Twenty-seven individuals, among them 18 patients with valvular stenosis, underwent AVA planimetry by both MSCT and MRI. In the subset of patients with valvular stenosis, AVA was also calculated from transthoracic Doppler echocardiography (TTE) using the continuity equation.
There was excellent correlation between MSCT and MRI (r = 0.99) and limits of agreement were in an acceptable range (± 0.42 cm(2)) although MSCT yielded a slightly smaller mean AVA than MRI (1.57 ± 0.83 cm(2) vs. 1.67 ± 0.98 cm(2), p < 0.05). However, in the subset of patients with valvular stenosis, the mean AVA was not different between MSCT and MRI (1.05 ± 0.30 cm(2) vs. 1.04 ± 0.39 cm(2); p > 0.05). The mean AVAs on both MSCT and MRI were systematically larger than on TTE (0.88 ± 0.28 cm(2), p < 0.001 each). Using an AVA of 1.0 cm(2) on TTE as reference, the best threshold for detecting severe-to-critical stenosis on MSCT and MRI was an AVA of 1.25 cm(2) and 1.30 cm(2), respectively, resulting in an accuracy of 96% each.
Our study specifies recent reports on the suitability of MSCT for quantifying AVA. The data presented here suggest that certain methodical discrepancies of AVA measurements exist between MSCT, MRI and TTE. However, MSCT and MRI have shown excellent correlation in AVA planimetry and similar accuracy in grading aortic valve stenosis.
我们旨在确定多层螺旋 CT(MSCT)和磁共振成像(MRI)在测量主动脉瓣口面积(AVA)和分级主动脉瓣狭窄方面的可比性。
27 名参与者,其中 18 名为瓣膜狭窄患者,同时接受了 MSCT 和 MRI 的 AVA 平面测量。在瓣膜狭窄患者亚组中,也使用经胸多普勒超声心动图(TTE)的连续方程计算 AVA。
MSCT 与 MRI 之间具有极好的相关性(r = 0.99),且一致性界限在可接受范围内(± 0.42 cm²),尽管 MSCT 得出的平均 AVA 略小于 MRI(1.57 ± 0.83 cm² 与 1.67 ± 0.98 cm²,p < 0.05)。然而,在瓣膜狭窄患者亚组中,MSCT 和 MRI 之间的平均 AVA 没有差异(1.05 ± 0.30 cm² 与 1.04 ± 0.39 cm²;p > 0.05)。MSCT 和 MRI 上的平均 AVA 均大于 TTE(0.88 ± 0.28 cm²,p < 0.001 各)。以 TTE 上的 1.0 cm²AVA 为参考,MSCT 和 MRI 检测严重至重度狭窄的最佳阈值分别为 1.25 cm²和 1.30 cm²,准确率均为 96%。
我们的研究明确了 MSCT 用于量化 AVA 的适用性的最新报告。这里提供的数据表明,MSCT、MRI 和 TTE 之间在 AVA 测量方面存在一定的方法学差异。然而,MSCT 和 MRI 在 AVA 平面测量方面显示出极好的相关性,在分级主动脉瓣狭窄方面具有相似的准确性。