Fulkerson J P, Ozonoff M B
AJR Am J Roentgenol. 1977 Aug;129(2):313-6. doi: 10.2214/ajr.129.2.313.
The clinical, laboratory, and radiologic picture of a unique patient with symmetrical fractures of the anterior tibial midshafts, dorsal ulnar cortices, and lateral metatarsals is presented. The findings are not compatible with a diagnosis of osteogenesis imperfecta or osteomalacia despite osseous fragility. The elevated serum pyrophosphate and low urine phosphate content suggest that abnormalities in phosphate metabolism may have contributed to the formation of bone which is biochemically and structurally deficient.
本文介绍了一位独特患者的临床、实验室及影像学表现，该患者胫骨中段前侧、尺骨背侧皮质及外侧跖骨出现对称性骨折。尽管存在骨质脆弱，但这些表现不符合成骨不全或骨软化症的诊断。血清焦磷酸盐升高和尿磷酸盐含量降低表明，磷酸盐代谢异常可能导致了生化和结构上存在缺陷的骨骼形成。
