Department of Rheumatology, Clinical Research Center for Rheumatic Disease, NHO Kumamoto Saishunsou National Hospital, 2659 Suya, Kohshi, Kumamoto, 861-1196, Japan.
Mod Rheumatol. 2010 Feb;20(1):77-80. doi: 10.1007/s10165-009-0228-3. Epub 2009 Sep 26.
A 76-year-old woman with seropositive rheumatoid arthritis (RA) developed acute respiratory distress syndrome (ARDS) following an appearance of severe inflammatory symptoms in multiple synovial joints. High-dose pulse therapy with methylprednisolone induced a marked improvement in pulmonary conditions. To the best of our knowledge, this is the first case in the literature to show a causal relationship between ARDS and RA. We should be alert to the possibility that ARDS can occur as an acute-type pulmonary complication of RA, particularly when patients show rapid aggravation of rheumatic activity.
一位 76 岁的女性，血清阳性类风湿关节炎（RA）患者，在多个滑膜关节出现严重炎症症状后发生急性呼吸窘迫综合征（ARDS）。甲泼尼龙大剂量脉冲疗法显著改善了肺部状况。据我们所知，这是文献中首例表明 ARDS 与 RA 之间存在因果关系的病例。我们应该警惕 ARDS 可能作为 RA 的一种急性型肺部并发症发生，特别是当患者的风湿活动迅速加重时。
