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Resolution of late sirolimus-eluting stent thrombosis after tirofiban treatment.

作者信息

Karakurt Ozlem, Cagirci Goksel, Kilic Harun, Akdemir Ramazan

机构信息

Department of Cardiology, Ministry of Health, Dişkapi Yildirim Beyazit Research and Education Hospital, Ankara, Turkey.

出版信息

Heart Vessels. 2009 Sep;24(5):388-90. doi: 10.1007/s00380-009-1149-y. Epub 2009 Sep 27.

DOI:10.1007/s00380-009-1149-y
PMID:19784825
Abstract

A 40-year-old male patient was admitted to the hospital with acute chest pain. A sirolimus-eluting stent (SES) had been deployed to the circumflex artery (Cx) 3 years before. Now, inferior ST-segment elevations were observed and coronary angiography revealed stent thrombosis with distal TIMI 3 grade flow in the Cx. Tirofiban infusion was administered and the control angiography 2 days later revealed complete resolution of the thrombus. Stent thrombosis is a rare but usually poor prognostic event, frequently associated with large myocardial infarction (MI) or death. Very late drug-eluting stent (DES) thrombosis remains a major problem of interventional cardiology due to its high morbidity and mortality. We conclude that tirofiban may be an interesting candidate drug for treatment of very late stent thrombosis.

摘要

相似文献

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本文引用的文献

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Urgent PCI in patients with stent thrombosis: an observational single-center study comparing thrombus aspiration and standard PCI.
J Invasive Cardiol. 2008 Apr;20(4):161-5.
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Effects of drug-eluting stents on systemic inflammatory response in patients with unstable angina pectoris undergoing percutaneous coronary intervention.药物洗脱支架对接受经皮冠状动脉介入治疗的不稳定型心绞痛患者全身炎症反应的影响。
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Risk factors for stent thrombosis after implantation of sirolimus-eluting stents in diabetic and nondiabetic patients: the EVASTENT Matched-Cohort Registry.糖尿病和非糖尿病患者西罗莫司洗脱支架植入术后支架内血栓形成的危险因素：EVASTENT匹配队列注册研究
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Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study.西罗莫司洗脱支架和紫杉醇洗脱支架在常规临床实践中的早期和晚期冠状动脉支架血栓形成：来自一项大型双机构队列研究的数据。
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