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普罗帕酮与索他洛尔同时给药期间的危及生命的室性心律失常

[Life-threatening ventricular arrhythmia during simultaneous administration of propafenone and sotatol].

作者信息

Gilewski Wojciech, Bednarska Dorota, Sinkiewicz Władysław

机构信息

Szpital Uniwersytecki nr 2 im. dr. J. Biziela, ul. Ujejskiego 75, 85-168 Bydgoszcz.

出版信息

Kardiol Pol. 2009 Aug;67(8):916-20; discussion 921.

PMID:19784892
Abstract

A case of a patient treated with antiarrhythmic drugs for ventricular arrhythmia occurring after viral infection of the respiratory tract is presented. In the course of preliminary cardiologic examination no organic heart disease was diagnosed. Due to numerous ventricular extrasystolic beats (16,500 per day) and short runs of non-sustained ventricular tachycardia (maximum of 4 subsequent beats) propafenone was introduced. Persistent arrhythmia was a reason for adding sotalol to that treatment in an outpatient clinic. After three weeks of such treatment the patient presented cardiac arrest in the mechanism of ventricular tachycardia and fibrillation. Successful resuscitation and drug discontinuation led to complete resolution of the life-threatening arrhythmia. No inducible complex ventricular arrhythmia was observed during electrophysiologic examination.

摘要

本文介绍了一例呼吸道病毒感染后发生室性心律失常并接受抗心律失常药物治疗的患者。在初步心脏检查过程中,未诊断出器质性心脏病。由于频发室性早搏(每天16500次)和短阵非持续性室性心动过速(最多连续4次搏动),开始使用普罗帕酮。持续性心律失常是在门诊将索他洛尔加入该治疗方案的原因。经过三周的这种治疗后,患者出现了室性心动过速和颤动机制的心脏骤停。成功复苏并停用药物后,危及生命的心律失常完全消失。在电生理检查期间未观察到可诱发的复杂性室性心律失常。

相似文献

1
[Life-threatening ventricular arrhythmia during simultaneous administration of propafenone and sotatol].普罗帕酮与索他洛尔同时给药期间的危及生命的室性心律失常
Kardiol Pol. 2009 Aug;67(8):916-20; discussion 921.
2
[Pharmacologic therapy of ventricular tachyarrhythmias: value of class III anti-arrhythmia drugs].[室性快速性心律失常的药物治疗:Ⅲ类抗心律失常药物的价值]
Z Kardiol. 1996;85 Suppl 6:97-106.
3
Ibutilide added to propafenone for the conversion of atrial fibrillation and atrial flutter.伊布利特联合普罗帕酮用于心房颤动和心房扑动的转复。
J Am Coll Cardiol. 2004 Aug 18;44(4):859-63. doi: 10.1016/j.jacc.2004.04.056.
4
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G Ital Cardiol. 1984 Sep;14(9):644-54.
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Sotalol: a new class III antiarrhythmic agent.索他洛尔:一种新型Ⅲ类抗心律失常药物。
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Broad complex tachycardia during treatment of atrial fibrillation with a 1c antiarrhythmic drug: ventricular or supraventricular proarrhythmia?使用Ⅰc类抗心律失常药物治疗心房颤动期间出现的宽QRS波群心动过速:室性还是室上性心律失常?
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