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抗精神病药物治疗中的认知障碍。

Cognitive disturbances in neuroleptic therapy.

作者信息

Strauss W H, Klieser E

机构信息

Department of Psychiatry, University of Düsseldorf, FRG.

出版信息

Acta Psychiatr Scand Suppl. 1990;358:56-7. doi: 10.1111/j.1600-0447.1990.tb05289.x.

Abstract

Eighteen patients (7 men, 11 women) from one of the centres taking part in a multicentre comparative study of remoxipride and haloperidol in the treatment of acute schizophrenia were investigated separately to study the effect of the two neuroleptic drugs on cognitive abilities. The tests of cognitive ability that were used are standard in West Germany. The results of this study indicate that there could be differences between remoxipride and haloperidol regarding their effects on cognitive abilities--the patients who had been treated for four weeks with remoxipride showed a greater "mental fitness".

摘要

参与一项关于瑞莫必利和氟哌啶醇治疗急性精神分裂症的多中心对比研究的其中一个中心的18名患者(7名男性,11名女性)被分别进行调查,以研究这两种抗精神病药物对认知能力的影响。所使用的认知能力测试在西德是标准测试。这项研究的结果表明,瑞莫必利和氟哌啶醇在对认知能力的影响方面可能存在差异——用瑞莫必利治疗四周的患者表现出更高的“精神健康水平”。

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