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[抗击新型甲型H1N1流感病毒。I. 相关病毒学方面概述]

[Combating the new influenza A (H1N1) virus. I. Overview of the relevant virological aspects].

作者信息

Koopmans Marion P G, Meijer Adam, van der Lubben Mariken I M, Boucher Charles, Fouchier Ron A M, Osterhaus Ab D M E, Timen Aura, de Jong Menno D, van Steenbergen Jim E

机构信息

Rijksinstituut voor Volksgezondheid en Milieu, Bilthoven, The Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2009;153:A770.

Abstract

In April 2009 a new influenza virus was discovered, which spread from Mexico to the rest of the world. The new influenza A (H1N1) virus is genetically related to swine flu viruses, and differs substantially from circulating human influenza viruses. It is able to spread from person to person. Because it is a completely new virus, there is probably little immunity in the population. The course of the infection is relatively mild, but the virus will mutate and it is not yet certain whether this will affect severity of the influenza. General practitioners have an important role in surveillance and treatment. The Community Health Services must be notified of any patients who are suspected of having the new influenza. Hygiene measures and administration of antiviral drugs to patients and their contacts may slow the spread. A delay in large-scale spread in the Netherlands allows time for the development of vaccines.

摘要

2009年4月,一种新型流感病毒被发现,它从墨西哥传播到世界其他地区。新型甲型H1N1流感病毒在基因上与猪流感病毒相关,与正在传播的人类流感病毒有很大不同。它能够在人与人之间传播。由于这是一种全新的病毒,人群中可能几乎没有免疫力。感染过程相对温和,但病毒会发生变异,目前尚不确定这是否会影响流感的严重程度。全科医生在监测和治疗中发挥着重要作用。任何疑似感染新型流感的患者都必须通知社区卫生服务机构。对患者及其接触者采取卫生措施并给予抗病毒药物治疗可能会减缓传播速度。荷兰大规模传播的延迟为疫苗的研发争取了时间。

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