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[神经血吸虫病;一名荷兰女性的意外发现]

[Neuroschistosomiasis; an unexpected finding in a Dutch woman].

作者信息

Bouwhuis Jolande W, van der Ven Andre J A M, Gijtenbeek Johanna M M, Wesseling Pieter, Sauerwein Robert W, Beckers Pieter J A

机构信息

Afd. Interne Geneeskunde en Infectieziekten, Universitair Medisch Centrum St Radboud, Nijmegen, The Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2009;153:A196.

PMID:19785826
Abstract

A 67-year-old Dutch woman presented with neurological symptoms of several months duration. MRI scans of the brain showed intracerebral lesions. Brain biopsy revealed granulomatous inflammation and remnants of worm eggs. Eggs of Schistosoma mansoni were found in the stools and serological tests were positive for Schistosoma. From additional history taking it became clear that the patient contracted schistosomiasis when visiting Brazil several years before. She was treated with praziquantel and corticosteroids. Neuroschistosomiasis is a rare but severe complication of Schistosoma infection. This diagnosis should be considered in patients that travelled to or originate from endemic schistosomiasis areas.

摘要

一名67岁的荷兰女性出现了持续数月的神经症状。脑部MRI扫描显示脑内有病变。脑活检显示肉芽肿性炎症和虫卵残留。粪便中发现了曼氏血吸虫卵,血清学检测显示血吸虫呈阳性。通过进一步询问病史发现,该患者几年前在访问巴西时感染了血吸虫病。她接受了吡喹酮和皮质类固醇治疗。神经血吸虫病是血吸虫感染的一种罕见但严重的并发症。对于去过血吸虫病流行地区或来自这些地区的患者,应考虑这一诊断。

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