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[结直肠癌筛查:首选粪便潜血免疫检测]

[Colorectal cancer screening: immunological test for faecal occult blood preferred].

作者信息

Jansen Jan B M J, van Rossum Leo G M, Laheij Robert J F

机构信息

Universitair Medisch Centrum St Radboud, afd. Maag-, Darm- en Leverziekten, Nijmegen, The Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2009;153:A474.

PMID:19785842
Abstract

In 2003, the European Commission advised the Member States to start colorectal cancer screening. More than 12 million Europeans have been tested to date, not only by means of faecal occult blood testing but often also by opportunistic endoscopy. Nearly all of the screening programmes concerned were opportunistic in nature. The Dutch government is currently considering the implementation of an organised screening programme for the detection of colorectal cancer. The question no longer seems to be whether a screening programme should be started but rather which screening test should be used. We argue that an immunological faecal occult blood test is to be preferred over other screening tests, such as endoscopy.

摘要

2003年,欧盟委员会建议成员国启动结直肠癌筛查。迄今为止,已有超过1200万欧洲人接受了检测,检测手段不仅包括粪便潜血检测,还常常采用机会性内镜检查。几乎所有相关的筛查项目本质上都是机会性的。荷兰政府目前正在考虑实施一项有组织的结直肠癌检测筛查项目。问题似乎不再是是否应该启动筛查项目,而是应该使用哪种筛查检测方法。我们认为,与其他筛查检测方法(如内镜检查)相比,免疫粪便潜血检测更值得优先选择。

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1
[Colorectal cancer screening: immunological test for faecal occult blood preferred].[结直肠癌筛查:首选粪便潜血免疫检测]
Ned Tijdschr Geneeskd. 2009;153:A474.
2
Limitations of the faecal occult blood test in screening for colorectal cancer.粪便潜血试验在结直肠癌筛查中的局限性。
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Nonmedical costs of colorectal cancer screening with the fecal occult blood test and colonoscopy.粪便潜血试验和结肠镜检查用于结直肠癌筛查的非医疗费用。
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Recommendations on population screening for colorectal cancer in New Zealand. Members of the National Health Committee Working Party on Population Screening for Colorectal Cancer.新西兰结直肠癌人群筛查建议。国家卫生委员会结直肠癌人群筛查工作组成员。
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Many participants in fecal occult blood test population screening have a higher-than-average risk for colorectal cancer.许多参与粪便潜血试验人群筛查的人患结直肠癌的风险高于平均水平。
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Faecal occult blood test-based screening programme with high compliance for colonoscopy has a strong clinical impact on colorectal cancer (Br J Surg 2009; 96: 533-540).基于粪便潜血试验且结肠镜检查依从性高的筛查项目对结直肠癌具有显著临床影响(《英国外科杂志》2009年;96: 533 - 540)。
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8
Can quantification of faecal occult blood predetermine the need for colonoscopy in patients at risk for non-syndromic familial colorectal cancer?对非综合征性家族性结直肠癌风险患者进行粪便潜血定量检测能否预先确定其是否需要进行结肠镜检查?
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9
Faecal occult blood test-based screening programme with high compliance for colonoscopy has a strong clinical impact on colorectal cancer.基于粪便潜血试验且结肠镜检查依从性高的筛查计划对结直肠癌具有重大临床影响。
Br J Surg. 2009 May;96(5):533-40. doi: 10.1002/bjs.6568.
10
Colorectal cancer screening using immunochemical faecal occult blood testing in Japan.日本采用免疫化学法粪便潜血检测进行结直肠癌筛查。
J Med Screen. 2006;13 Suppl 1:S6-7.