Vroegop J Sebastiaan, Aalbers René, van Loon Aren J
Martini Ziekenhuis, Afd. Longziekten, Groningen, The Netherlands.
Ned Tijdschr Geneeskd. 2009;153:B361.
Treatment of asthma during pregnancy leads to discussion concerning medication and complications of pregnancy.Insecurity about possible teratogenity leads in the first trimester in 40% of pregnant women to reduction or cessation of asthma medication.This results, in pregnant women with moderate to severe asthma, in an increased consumption of rescue medication and number of exacerbations, and reduced asthma control. Asthma-exacerbations are significantly correlated with low birthweight. Of the majority of asthma medications, consumption during pregnancy has not been shown to cause harmful effects on the foetus. Adequate therapy for maintenance and exacerbations are essential, noting that the treatment in essence should not differ between pregnant and nonpregnant asthmatic women. A preconceptional consultation by a pulmonary physician and gynaecologist could improve care for pregnant women with asthma.
孕期哮喘的治疗引发了关于药物治疗及妊娠并发症的讨论。对潜在致畸性的担忧致使40%的孕妇在孕早期减少或停用哮喘药物。这使得中重度哮喘孕妇增加了急救药物的使用量及病情加重次数,哮喘控制情况变差。哮喘发作与低出生体重显著相关。多数哮喘药物在孕期使用尚未显示对胎儿有有害影响。维持治疗及控制病情加重的充分治疗至关重要,需注意的是,本质上孕妇与非孕妇哮喘患者的治疗并无差异。由肺科医生和妇科医生进行孕前咨询有助于改善对哮喘孕妇的护理。