Leenarts Marjolein F E, Blaauwgeers Hans L G, Hoekzema Rick
Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Huidziekten, Amsterdam, The Netherlands.
Ned Tijdschr Geneeskd. 2009;153:A285.
A 33-year-old woman presented with a 5-year history of a relapsing erythematous, indurated plaque on the left cheek. Herpes simplex virus (HSV) immunostain revealed the presence of HSV in the follicular and perifollicular keratinocytes. After oral treatment with valaciclovir for a period of 3 months the lesion disappeared without leaving a scar. At the last check-up, no recurrence had occurred. Herpes folliculitis has various clinical presentations. In rare cases it mimics a pseudolymphoma, as was the case for this patient. A viral aetiology, such as HSV or varicella-zoster virus, should be considered in patients with folliculitis, especially when the condition does not respond to antibacterial and antifungal therapy.
一名33岁女性,左侧脸颊出现反复复发的红斑性硬结斑块5年。单纯疱疹病毒(HSV)免疫染色显示在毛囊及毛囊周围角质形成细胞中有HSV存在。口服伐昔洛韦治疗3个月后,皮损消失,未留瘢痕。在最后一次检查时,未出现复发。疱疹性毛囊炎有多种临床表现。在罕见情况下,它可类似假性淋巴瘤,该患者即属此例。对于毛囊炎患者,尤其是对抗菌和抗真菌治疗无反应时,应考虑病毒病因,如HSV或水痘-带状疱疹病毒。