部分保护油菜素内酯的制备及合成应用。

Preparation and synthetic application of partially protected brassinosteroids.

机构信息

Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Kuprevich str., 5/2, 220141 Minsk, Belarus.

出版信息

Steroids. 2010 Jan;75(1):27-33. doi: 10.1016/j.steroids.2009.09.010. Epub 2009 Sep 26.

DOI:10.1016/j.steroids.2009.09.010

PMID:19786042

Abstract

Preparation of partially protected brassinosteroids is achieved through the reaction of the source material (24-epicastasterone and 24-epibrassinolide) with diol-specific reagents (2,2-dimethoxypropane and methylboronic acid). The obtained products were shown to be useful synthetic intermediates for further preparation of minor representatives of this class of natural phytohormones (such as 3,24-diepicastasterone and 3-dehydro-24-epibrassinolide).

摘要

部分保护的油菜素内酯的制备是通过与二醇特异性试剂（2,2-二甲氧基丙烷和甲基硼酸）反应源材料（24-表高油菜素内酯和 24-表油菜素内酯）来实现的。所得到的产物被证明是进一步制备该类天然植物激素的次要代表（如 3,24-表高油菜素内酯和 3-去氢 24-表油菜素内酯）的有用的合成中间体。