Obstetrics and Gynecology Department, St Pierre University Hospital, Rue Haute 322, 1000 Brussels, Belgium.
Eur J Obstet Gynecol Reprod Biol. 2009 Dec;147(2):226-9. doi: 10.1016/j.ejogrb.2009.09.003. Epub 2009 Sep 27.
Adequate staging of advanced cervical cancer is essential in order to optimally treat the patient. FIGO clinical staging, imaging techniques such as CT scan, MRI and PET sometimes underestimate the extension of tumors. The presence of para-aortic lymph node metastases in advanced cervical cancer identifies patients with poor prognosis who need to be treated aggressively. Laparoscopic para-aortic lymph node dissection is now proposed as a diagnostic tool in many guidelines. We evaluated the feasibility and safety of a robot assisted laparoscopic transperitoneal approach to para-aortic lymph node dissection.
Eight patients with advanced cervical carcinoma who were eligible for primary pelvic radiotherapy combined with concurrent cisplatin chemotherapy or pelvic exenteration underwent a pre-treatment robot assisted transperitoneal laparoscopic para-aortic lymphadenectomy.
We isolated from 1 to 38 para-aortic nodes per patient and had one para-aortic node positive patient who was treated with extended doses of pelvic radiotherapy. We did not encounter any major complications and post-operative morbidity was low.
Robot assisted transperitoneal laparoscopic para-aortic lymphadenectomy is feasible and provides the surgeon with greater precision than classical laparoscopy. Larger prospective multicentric trials are needed to validate the generalised usefulness of this technique.
为了对患者进行最佳治疗,充分进行晚期宫颈癌分期至关重要。FIGO 临床分期、CT 扫描、MRI 和 PET 等影像学技术有时会低估肿瘤的扩展程度。晚期宫颈癌中存在腹主动脉旁淋巴结转移的患者,预后较差,需要积极治疗。腹腔镜腹主动脉旁淋巴结清扫术现在已被许多指南推荐为一种诊断工具。我们评估了机器人辅助腹腔镜经腹腔途径进行腹主动脉旁淋巴结清扫的可行性和安全性。
8 例适合接受原发性骨盆放疗联合顺铂同期化疗或骨盆切除术治疗的晚期宫颈癌患者,在术前接受了机器人辅助经腹腔腹腔镜腹主动脉旁淋巴结切除术。
我们从每位患者中分离出 1 至 38 个腹主动脉旁淋巴结,有 1 例腹主动脉旁淋巴结阳性的患者接受了扩展剂量的盆腔放疗。我们没有遇到任何严重并发症,术后发病率较低。
机器人辅助经腹腔腹腔镜腹主动脉旁淋巴结清扫术是可行的,为外科医生提供了比传统腹腔镜更高的精度。需要更大规模的前瞻性多中心试验来验证该技术的普遍适用性。