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Selection bias is not a good reason for advising more than 5 years of adjuvant hormonal therapy for all patients with locally advanced prostate cancer treated with radiotherapy.

作者信息

Collette Laurence, Studer Urs E

出版信息

J Clin Oncol. 2009 Nov 20;27(33):e201-2; author reply e204. doi: 10.1200/JCO.2009.23.3601. Epub 2009 Sep 28.

DOI:10.1200/JCO.2009.23.3601
PMID:19786659
Abstract
摘要

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Selection bias is not a good reason for advising more than 5 years of adjuvant hormonal therapy for all patients with locally advanced prostate cancer treated with radiotherapy.对于所有接受放疗的局部晚期前列腺癌患者，选择偏倚并非建议进行超过5年辅助激素治疗的充分理由。
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Delayed rectal and urinary symptomatology in patients treated for prostate cancer by radiotherapy with or without short term neo-adjuvant androgen deprivation.接受放疗（无论有无短期新辅助雄激素剥夺治疗）的前列腺癌患者出现延迟性直肠和泌尿系统症状。
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Risk-adapted androgen deprivation and escalated three-dimensional conformal radiotherapy for prostate cancer: Does radiation dose influence outcome of patients treated with adjuvant androgen deprivation? A GICOR study.风险适应性雄激素剥夺与强化三维适形放疗治疗前列腺癌：放疗剂量是否影响接受辅助雄激素剥夺治疗患者的结局？一项GICOR研究。
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A randomized trial comparing radical prostatectomy plus endocrine therapy versus external beam radiotherapy plus endocrine therapy for locally advanced prostate cancer: results at median follow-up of 102 months.一项比较根治性前列腺切除术加内分泌治疗与外照射放疗加内分泌治疗对局部晚期前列腺癌疗效的随机试验：中位随访102个月的结果
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Risks and benefits of hormonal manipulation as monotherapy or adjuvant treatment in localised prostate cancer.激素治疗作为局限性前列腺癌单一疗法或辅助治疗的风险与益处
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Intermittent androgen deprivation for locally advanced and metastatic prostate cancer: results from a randomised phase 3 study of the South European Uroncological Group.间歇性雄激素剥夺疗法治疗局部晚期和转移性前列腺癌：来自南欧泌尿肿瘤学组的一项随机3期研究结果
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Long-term follow-up of patients with prostate cancer and nodal metastases treated by pelvic lymphadenectomy and radical prostatectomy: the positive impact of adjuvant radiotherapy.接受盆腔淋巴结清扫术和根治性前列腺切除术治疗的前列腺癌伴淋巴结转移患者的长期随访：辅助放疗的积极影响
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