Department of Nephrology and Hypertension, University of Erlangen-Nuremberg, Krankenhausstrasse 12, Erlangen, Germany.
Nat Rev Nephrol. 2009 Nov;5(11):650-7. doi: 10.1038/nrneph.2009.153. Epub 2009 Sep 29.
Kidney Disease: Improving Global Outcomes (KDIGO) is an independent organization with the mission to improve care and outcomes of patients with kidney disease worldwide through the development and coordination of clinical practice guidelines. KDIGO has established firm links with other organizations that have previously produced clinical practice guidelines in the field of kidney disease. The first three KDIGO guidelines--treatment of hepatitis C, management of bone and mineral disease, and care of kidney transplant recipients--have been finalized and the next three--acute kidney injury, management of glomerulonephritis, and management of blood pressure in chronic kidney disease--are under development. The ultimate goal is to cover most major aspects of care for patients with kidney disease. Corner stones of KDIGO's guideline development process are independent, multidisciplinary, international work groups, close collaboration with professional methodology experts who perform systematic evidence reviews, and open public review of each guideline. Grades of Recommendation Assessment, Development, and Evaluation (GRADE) methodology is applied for grading the quality of evidence and strength of recommendations. International conferences organized by KDIGO support the coordination of guideline development, assess the suitability of guideline topics and help to establish global consensus on definitions and policies.
改善全球肾脏病预后组织（KDIGO）是一个独立的组织，其使命是通过制定和协调肾脏病临床实践指南，改善全球范围内肾脏病患者的护理和结局。KDIGO 与其他之前在肾脏病领域制定临床实践指南的组织建立了牢固的联系。前三个 KDIGO 指南——丙型肝炎的治疗、骨和矿物质疾病的管理以及肾移植受者的护理——已经定稿，接下来的三个指南——急性肾损伤、肾小球肾炎的管理以及慢性肾脏病中的血压管理——正在制定中。最终目标是涵盖肾脏病患者护理的大多数主要方面。KDIGO 指南制定过程的基石是独立的、多学科的国际工作组，与专业方法学专家密切合作，进行系统的证据审查，并对每个指南进行公开审查。推荐评估、制定和评价（GRADE）方法学用于对证据质量和推荐强度进行分级。KDIGO 组织的国际会议支持指南制定的协调，评估指南主题的适宜性，并有助于就定义和政策达成全球共识。
