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酷似腹膜后纤维化的局限性腹膜后淀粉样变性:梗阻性尿路病的罕见病因。

Localised retroperitoneal amyloidosis mimicking retroperitoneal fibrosis: a rare cause of obstructive uropathy.

作者信息

Banerji J S, Gopalakrishnan G, Sriram K, Manipadam M T

机构信息

Department of Urology, Christian Medical College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India.

出版信息

Singapore Med J. 2009 Sep;50(9):e332-5.

Abstract

Primary localised amyloidosis involving the retroperitoneum is a rare disease. We report a 71-year-old diabetic man who presented with generalised fatigue, malaise and elevated serum creatinine. Investigations confirmed obstructive uropathy secondary to a retroperitoneal mass behind the urinary bladder, causing extrinsic compression of both the ureters, resulting in bilateral hydroureteronephrosis. Following initial bilateral percutaneous nephrostomies to stabilise renal function, a computed tomography-guided biopsy of the pelvic lesion which was done, was suggestive of amyloidosis. We present this case due to the rarity of localised retroperitoneal amyloidosis as a cause of obstructive uropathy.

摘要

原发性局限性腹膜后淀粉样变性是一种罕见疾病。我们报告一例71岁糖尿病男性患者,其表现为全身乏力、不适及血清肌酐升高。检查证实为膀胱后方腹膜后肿块继发梗阻性尿路病,导致双侧输尿管受到外部压迫,进而引起双侧肾盂积水。在最初进行双侧经皮肾造瘘术以稳定肾功能后,对盆腔病变进行了计算机断层扫描引导下的活检,结果提示为淀粉样变性。鉴于局限性腹膜后淀粉样变性作为梗阻性尿路病病因的罕见性,我们报告了此病例。

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