Section of Neuroradiology, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Neurosurg Rev. 2010 Jan;33(1):115-9. doi: 10.1007/s10143-009-0227-z. Epub 2009 Sep 29.
Intracerebral arteriovenous malformations (AVMs) are traditionally recognized as congenital lesions. However, with the advent of frequent, noninvasive imaging of the brain, that notion has been challenged. We describe another patient with a de novo cerebral arteriovenous malformation and evaluate the reported literature for trends in the development of these lesions. Cases were selected from the English literature using the PUBMED database using the search term "acquired or de novo cerebrovascular arteriovenous malformations". A total of seven patients (including the one reported in this study) with de novo arteriovenous malformations are reported. Majority of patients were female, and mostly diagnosed as children. Their mean age at diagnosis was 18 years (6-32), and the mean time from the initial intracranial study to the diagnosis of an AVM was 8 years (3-17). De novo formation of AVMs is being increasingly reported, especially in young females. We present only the seventh such case reported in the literature and challenge the traditional view that all arteriovenous malformations are congenital in nature.
颅内动静脉畸形（AVM）传统上被认为是先天性病变。然而，随着大脑频繁进行非侵入性成像，这一观点受到了挑战。我们描述了另一位患有新发脑动静脉畸形的患者，并评估了报告的文献中这些病变发展的趋势。使用 PUBMED 数据库中的英文文献，使用搜索词“获得性或新发脑血管动静脉畸形”选择病例。共报告了 7 例（包括本研究报告的 1 例）新发动静脉畸形患者。大多数患者为女性，大部分诊断为儿童。他们的诊断时平均年龄为 18 岁（6-32 岁），从首次颅内研究到诊断动静脉畸形的平均时间为 8 年（3-17 年）。新发动静脉畸形的形成越来越多，尤其是在年轻女性中。我们仅报告了文献中第七例此类病例，并对所有动静脉畸形本质上都是先天性的传统观点提出了挑战。
