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青光眼患者中新型3D计算机自动阈值阿姆斯勒方格视野检测暗点的研究

Novel 3D computer-automated threshold Amsler grid visual field testing of scotomas in patients with glaucoma.

作者信息

Nguyen Dieuthu T, Fahimi Ali, Fink Wolfgang, Nazemi Paul P, Kim Janet K, Sadun Alfredo A

机构信息

Doheny Eye Institute and Keck School of Medicine at the University of Southern California, Los Angeles, CA 90033, USA.

出版信息

Eur J Ophthalmol. 2009 Sep-Oct;19(5):776-82. doi: 10.1177/112067210901900515.

Abstract

PURPOSE

Three-dimensional (3D) computer-automated threshold Amsler grid testing was used to identify and characterize scotomas typical of glaucoma.

METHODS

The 3D test exhibits a grid on a computer screen at a preselected grayscale and angular resolution, and allows patients to trace those areas on the grid that are missing in their visual field using a touch screen. Eleven eyes in patients with an established diagnosis of glaucoma were examined according to the above protocol. A total of 23 eyes from normal subjects were used as controls. The 5-minute test required that patients repeatedly outline scotomas on a touch screen with varied displays of contrast while maintaining their gaze on a central fixation marker. A 3D depiction of the visual field defects was then obtained that was further characterized by the location, shape, extent, depth, and slope of the scotomas.

RESULTS

In this pilot study, the 3D depiction of visual field loss demonstrated paracentral, superior and inferior altitudinal, and nasal step defects consistent with glaucomatous damage. The 3D depiction showed a shape, extent, depth, and slope that are consistent with the severity of damage.

CONCLUSIONS

The 3D test identified and characterized scotomas typical of glaucoma. The test provides several advantages over conventional perimetry including additional information through 3D depiction of scotomas with the addition of contrast sensitivity and a higher angular/spatial resolution. Improved patient compliance and reliability through shorter testing time and potential interactive accessibility and distribution over the Internet further characterize the test.

摘要

目的

采用三维(3D)计算机自动阈值阿姆斯勒方格测试来识别和描述青光眼典型的暗点。

方法

3D测试在计算机屏幕上以预先选定的灰度和角分辨率显示一个方格,并允许患者使用触摸屏描绘出他们视野中缺失的方格区域。按照上述方案对11例已确诊青光眼患者的眼睛进行了检查。共使用23例正常受试者的眼睛作为对照。5分钟的测试要求患者在触摸屏上反复勾勒暗点,同时保持注视中央固定标记,屏幕上显示不同对比度的图像。然后获得视野缺损的3D描绘,并通过暗点的位置、形状、范围、深度和斜率进一步进行特征描述。

结果

在这项初步研究中,视野缺损的3D描绘显示出与青光眼性损害一致的旁中心、上下象限性和鼻侧阶梯状缺损。3D描绘显示出与损害严重程度一致的形状、范围、深度和斜率。

结论

3D测试识别并描述了青光眼典型的暗点。该测试相对于传统视野检查具有多个优势,包括通过暗点的3D描绘提供额外信息,以及增加对比度敏感度和更高的角/空间分辨率。通过更短的测试时间提高患者依从性和可靠性,以及潜在的互联网交互式可及性和传播性进一步体现了该测试的特点。

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