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在椎实螺(Lymnaea stagnalis)的中枢神经系统中,儿茶酚胺的分布以及对诸如用于儿茶酚胺合成的脊椎动物酶等物质的免疫反应性。

Distribution of catecholamines and of immunoreactivity to substances like vertebrate enzymes for the synthesis of catecholamines within the central nervous system of the snail, Lymnaea stagnalis.

作者信息

Croll R P, Chiasson B J

机构信息

Department of Physiology and Biophysics, Faculty of Medicine, Dalhousie University, Halifax, N.S., Canada.

出版信息

Brain Res. 1990 Aug 13;525(1):101-14. doi: 10.1016/0006-8993(90)91325-b.

Abstract

Catecholamines (CAs) were detected histochemically within over 185 cell bodies in the central nervous system (CNS) of juvenile and young adult Lymnaea. This distribution of CA-containing cells in all central ganglia except the pleural ganglia is more widespread than previously described but is consistent with other reports suggesting numerous roles for CAs within the nervous system. This study also describes the distribution of substances which are antigenically similar to four bovine enzymes for catecholamine synthesis, but the distribution patterns showed little or no overlap with each other or with CA. These results suggest the need for caution in the interpretation of such immunohistochemical studies.

摘要

在幼年和成年初期的椎实螺中枢神经系统(CNS)中,通过组织化学方法检测到185个以上细胞体内含有儿茶酚胺(CAs)。除胸膜神经节外,含CA细胞在所有中枢神经节中的这种分布比先前描述的更为广泛,但与其他表明CAs在神经系统中具有多种作用的报告一致。本研究还描述了与四种牛儿茶酚胺合成酶抗原相似的物质的分布,但分布模式彼此之间或与CA几乎没有重叠。这些结果表明,在解释此类免疫组织化学研究时需要谨慎。

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