Hallstrand Teal S, Martin Diane P, Hummel Jeffery P, Williams Barbara L, LoGerfo James P
Department of Medicine, University of Washington, Seattle, Washington 98195, USA.
Ann Allergy Asthma Immunol. 2009 Sep;103(3):225-32. doi: 10.1016/S1081-1206(10)60186-X.
The Seattle Asthma Severity and Control Questionnaire (SASCQ) was designed as a short, sensitive, and quantitative measure of asthma severity, impairment, and risk.
To evaluate the distribution of responses to the SASCQ in a diverse asthma population and to determine whether the questionnaire is associated with other measures of asthma severity and control.
A cross-sectional study of 188 asthmatic patients was conducted in a large academic primary care network. Asthma severity was confirmed in a subgroup of 44 patients by means of an in-person interview and lung function measurement.
The SASCQ score had a nearly normal distribution across the heterogeneous population and less of a floor effect than the number of asthma-free days. The SASCQ score showed a higher symptom burden in the mildest asthmatic patients compared with nonasthmatic controls. Asthma severity evaluated using the questionnaire was correlated with asthma severity evaluated by means of in-person interview and with controller medication class. The SASCQ score was associated with primary care visits for asthma, emergency department treatment for asthma, days missed from work, and confidence to control asthma symptoms; the associations between these measures of impairment and risk were all stronger for the SASCQ score than for asthma-free days.
The SASCQ is a quantitative measure of asthma that accurately discriminates between established levels of asthma severity and that is associated with other measures of asthma control and risk.
西雅图哮喘严重程度与控制问卷（SASCQ）旨在作为一种简短、灵敏且定量的哮喘严重程度、损害及风险评估工具。
评估不同哮喘患者群体对SASCQ的应答分布情况，并确定该问卷是否与其他哮喘严重程度及控制的评估指标相关。
在一个大型学术性初级保健网络中对188例哮喘患者进行了一项横断面研究。通过面对面访谈和肺功能测量对44例患者亚组的哮喘严重程度进行了确认。
SASCQ评分在异质性人群中呈近似正态分布，且与无哮喘天数相比，地板效应较小。与非哮喘对照组相比，SASCQ评分显示最轻度哮喘患者的症状负担更高。使用该问卷评估的哮喘严重程度与通过面对面访谈评估的哮喘严重程度以及控制药物类别相关。SASCQ评分与哮喘的初级保健就诊、哮喘的急诊科治疗、误工天数以及控制哮喘症状的信心相关；这些损害和风险评估指标与SASCQ评分之间的关联均比与无哮喘天数之间的关联更强。
SASCQ是一种哮喘的定量评估工具，能够准确区分既定的哮喘严重程度水平，且与其他哮喘控制及风险评估指标相关。
