Mesfin F B, Drazin D, Berry S, Homan S, Nazeer T, German J W
The Neurosciences Institute, Division of Neurosurgery, Albany Medical Center, New York 12208, USA.
Clin Neuropathol. 2009 Sep-Oct;28(5):395-9. doi: 10.5414/npp28395.
A 72-year-old right-handed woman presented with a 6-month history of right thoracic wall discomfort. An MRI of the thoracic spine showed a small dumbbell-shaped mass centered within the right T7-8 foramen. The patient was asked to return to clinic for reevaluation to include a new MRI of the thoracic spine in 6 months. She did not comply with this recommendation and 1 year later, she presented with increasing difficulty ambulating and spastic paraparesis. A follow-up MRI of the thoracic spine now demonstrated significant interval growth of the mass with an extra-foraminal component extending into the thoracic cavity. She was taken to the operating room for resection of the epidural tumor. The pathology was consistent with diffuse follicle center lymphoma as cells were immunohistologically positive for CD20, CD 10, BCL-2 and BCL-6. Primary spinal follicle center lymphomas of the spine are rare with the current case being the first diffuse follicle center type reported in the literature.
一名72岁右利手女性，有6个月的右胸壁不适病史。胸椎MRI显示一个小哑铃形肿块，位于右侧T7-8椎间孔内。患者被要求返回诊所进行重新评估，包括6个月后进行新的胸椎MRI检查。她未遵循此建议，1年后，她出现行走困难加重和痉挛性截瘫。胸椎的随访MRI现在显示肿块有显著的间隔生长，有一个椎间孔外成分延伸至胸腔。她被送往手术室切除硬膜外肿瘤。病理结果与弥漫性滤泡中心淋巴瘤一致，因为细胞免疫组化CD20、CD10、BCL-2和BCL-6呈阳性。原发性脊柱滤泡中心淋巴瘤很少见，本例是文献中报道的首例弥漫性滤泡中心型。
