Shi Jinjie, Ahmed Daniel, Mao Xiaole, Lin Sz-Chin Steven, Lawit Aitan, Huang Tony Jun
Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Lab Chip. 2009 Oct 21;9(20):2890-5. doi: 10.1039/b910595f. Epub 2009 Aug 5.
Here we present an active patterning technique named "acoustic tweezers" that utilizes standing surface acoustic wave (SSAW) to manipulate and pattern cells and microparticles. This technique is capable of patterning cells and microparticles regardless of shape, size, charge or polarity. Its power intensity, approximately 5x10(5) times lower than that of optical tweezers, compares favorably with those of other active patterning methods. Flow cytometry studies have revealed it to be non-invasive. The aforementioned advantages, along with this technique's simple design and ability to be miniaturized, render the "acoustic tweezers" technique a promising tool for various applications in biology, chemistry, engineering, and materials science.
在此，我们展示了一种名为“声镊”的主动图案化技术，该技术利用表面驻波声波（SSAW）来操纵细胞和微粒并形成图案。这种技术能够对细胞和微粒进行图案化，而无论其形状、大小、电荷或极性如何。其功率强度比光镊低约5×10⁵倍，与其他主动图案化方法相比具有优势。流式细胞术研究表明它是非侵入性的。上述优点，再加上该技术设计简单且能够小型化，使得“声镊”技术成为生物学、化学、工程和材料科学等各种应用中有前景的工具。
