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可移动表面声波镊子:用于微操纵的多功能工具箱。

Movable surface acoustic wave tweezers: a versatile toolbox for micromanipulation.

作者信息

Qin Xianming, Liu Xianglian, Liu Shuo, Zhang Chuanyu, Bai Ningning, Li Xue, Wang Weidong, Liu Dan, Yang Qiqi, Yang Ruiguo, Shen Yajing, Wei Xueyong

机构信息

School of Mechano-Electronic Engineering, Xidian University, Xi'an, 710071, China.

State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an, 710049, China.

出版信息

Microsyst Nanoeng. 2024 Oct 28;10(1):155. doi: 10.1038/s41378-024-00777-3.

Abstract

Surface acoustic wave (SAW) tweezers are a promising multifunctional micromanipulation method that controls microscale targets via patterned acoustic fields. Owing to their device structure and bonding process, most SAW tweezers have limitations in terms of controlling the position and motion of the acoustic traps, as they generate an acoustic field with a fixed region and adjust the manipulation effects via signal modulation. To address this challenge, we propose movable SAW tweezers with a multilayer structure, achieving dynamic control of their wave field and acoustic trap positions; we demonstrate their precise manipulation functions, such as translation, in-plane rotation, out-of-plane rotation, and cluster formation, on a wide spectrum of samples, including particles, bubbles, droplets, cells, and microorganisms. Our method not only improves the degree of freedom and working range of SAW tweezers but also allows for precise and selective manipulation of microtargets via microtools and localized wavefields. Owing to their flexibility, versatility, and biocompatibility, the movable SAW tweezers can be a practical platform for achieving arbitrary manipulation of microscale targets and have the potential to play significant roles in biomedical microrobotics.

摘要

表面声波(SAW)镊子是一种很有前途的多功能微操纵方法,它通过图案化声场来控制微观尺度的目标。由于其器件结构和键合工艺,大多数SAW镊子在控制声陷阱的位置和运动方面存在局限性,因为它们产生的声场区域是固定的,并通过信号调制来调整操纵效果。为应对这一挑战,我们提出了一种具有多层结构的可移动SAW镊子,实现了对其波场和声陷阱位置的动态控制;我们展示了它们在包括颗粒、气泡、液滴、细胞和微生物在内的各种样品上的精确操纵功能,如平移、面内旋转、面外旋转和团聚形成。我们的方法不仅提高了SAW镊子的自由度和工作范围,还允许通过微工具和局部波场对微目标进行精确和选择性操纵。由于其灵活性、多功能性和生物相容性,可移动SAW镊子可以成为实现对微观尺度目标进行任意操纵的实用平台,并有可能在生物医学微机器人领域发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e10/11519341/cf16e0ed9b3b/41378_2024_777_Fig1_HTML.jpg

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