Department of Radiology, Freeman Hospital, Newcastle upon Tyne, UK.
Eur Radiol. 2010 Apr;20(4):908-14. doi: 10.1007/s00330-009-1614-0. Epub 2009 Sep 30.
The purpose of this study was to determine whether offline reported three-dimensional ultrasound (3DUS) is as accurate as standard two-dimensional ultrasound (2DUS) with regard to demonstrating gallbladder disease.
The cohort comprised 80 consecutive patients referred for an abdominal ultrasound examination. The participants underwent routine 2DUS assessment of the gallbladder followed by the acquisition of two 3DUS volumes of the region of the gall bladder. The two techniques were reported independently of each other, and the diagnoses were compared for correlation.
There was overall agreement of the two techniques in 89% of cases with a positive predictive value of 89%, negative predictive value of 91% and a specificity of 86%. Small polyps (sub-4 mm) were the only positive discrepancies. Cohen's kappa found that there was substantial agreement between the two techniques (p = 0.05 for a two-tailed kappa 0.67), and chi-squared test found no significant difference in diagnoses (p = 0.95).
This study shows that 3DUS diagnosis correlates well with 2DUS with regard to most gallbladder problems and could be sufficient as a stand-alone technique.
本研究旨在确定离线报告的三维超声（3DUS）在显示胆囊疾病方面是否与标准二维超声（2DUS）一样准确。
该队列包括 80 例连续接受腹部超声检查的患者。参与者接受常规的 2DUS 评估胆囊，然后获取胆囊区域的两个 3DUS 容积。这两种技术是相互独立报告的，比较诊断结果以进行相关性分析。
两种技术的总体一致性为 89%，阳性预测值为 89%，阴性预测值为 91%，特异性为 86%。只有小息肉（<4 毫米）的诊断结果存在阳性差异。Cohen's kappa 发现两种技术之间存在实质性一致性（双侧 kappa 值为 0.67，p=0.05），卡方检验发现诊断结果无显著差异（p=0.95）。
本研究表明，3DUS 诊断与 2DUS 相比，在大多数胆囊问题上相关性良好，可作为独立技术使用。
