Lögters T, Hakimi M, Windolf J, Schädel-Höpfner M
Klinik für Unfall- und Handchirurgie, Universitätsklinikum Düsseldorf, Moorenstrasse 5, Düsseldorf.
Handchir Mikrochir Plast Chir. 2009 Oct;41(5):271-6. doi: 10.1055/s-0029-1238295. Epub 2009 Sep 29.
The aim of this study was to evaluate, whether early and radical debridement for hand infections within a single operation followed by at most one second-look revision, is considered as sufficient to heal the infection or not. As one revision followed by at most one second-look revision is not successful for all cases, the value of defined variables on the clinical course and their clinical relevance were evaluated.
In this prospective study 50 patients (Mean age: 44; SD: 18 years of age) were included, who underwent surgical treatment in our hospital for severe infection of the hand. The individual course of each patient was documented. Patients, who needed more than two operations to heal the infection (group B) were compared with patients, who underwent one operation followed by at most one second-look revision (group A) under consideration of cause of infection, microbiology, pretreatment, preexistent diseases, and C-reactive protein.
Mean inpatient treatment lasted 19.3 (SD: 19.2) days. Patients underwent 4.4 operations (range: 1-24). For infect healing 22 of the 50 patients (group A) required 1-2 surgical revisions. For 28 patients (group B) more than 2 revisions were necessary. For patients of group B the cause for the infection was more often unknown (p<0.05). Patients who already underwent pretreatment externally showed a significantly increased risk for a prolonged course (p<0.05). A preexistent disease or an increase of CRP had no significant influence on the healing process (p>0.05).
Even if the concept of early and radical surgical debridement is consistently and adequately realized, healing of hand infection was achieved in less than 50% of the cases with one revision followed by at most one second-look revision. Particularly patients, who already underwent pretreatment externally before evaluation of a hand surgeon seem to be inclined to a prolonged courses of treatment.
本研究的目的是评估对于手部感染在单次手术中进行早期彻底清创,随后最多进行一次二次探查修复,是否足以治愈感染。由于一次修复后最多进行一次二次探查修复并非对所有病例都成功,因此评估了特定变量对临床病程的价值及其临床相关性。
在这项前瞻性研究中,纳入了50例患者(平均年龄:44岁;标准差:18岁),他们在我院因手部严重感染接受了手术治疗。记录了每位患者的个体病程。在考虑感染原因、微生物学、预处理、既往疾病和C反应蛋白的情况下,将需要进行两次以上手术才能治愈感染的患者(B组)与接受一次手术随后最多进行一次二次探查修复的患者(A组)进行比较。
平均住院治疗时间为19.3天(标准差:19.2天)。患者接受了4.4次手术(范围:1 - 24次)。为实现感染愈合,50例患者中的22例(A组)需要进行1 - 2次手术修复。2