Jeste D V, Krull A J, Kilbourn K
University of California, San Diego.
Geriatrics. 1990 Dec;45(12):49-54.
Neuroleptics are useful medications for the treatment of psychosis and severe behavioral disturbances in the elderly. Unfortunately, older patients are at a high risk of developing deleterious side effects from these medications, especially persistent tardive dyskinesia (TD). Diagnosis, risk factors, and cause and treatment of TD are discussed. It is important to do a careful assessment as to the indications for neuroleptic use, monitor closely for the development of TD and other side effects, and work closely with the patient and family in making decisions about neuroleptic use.
抗精神病药物是治疗老年人精神病和严重行为障碍的有效药物。不幸的是,老年患者使用这些药物出现有害副作用的风险很高,尤其是持续性迟发性运动障碍(TD)。本文讨论了TD的诊断、危险因素、病因及治疗。谨慎评估抗精神病药物的使用指征、密切监测TD及其他副作用的发生,并与患者及其家属密切合作以做出抗精神病药物使用的决策,这些都很重要。