Department of Neurosurgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, Shandong 250012, China.
J Clin Neurosci. 2009 Dec;16(12):1555-9. doi: 10.1016/j.jocn.2009.02.028. Epub 2009 Sep 29.
Microvascular decompression (MVD) is now a standard treatment for trigeminal neuralgia (tic douloureux). The goal of MVD is to decompress the trigeminal root from offending vessels, aiming at a permanent cure with no or little sensory deficit. Preoperative identification of neurovascular compression, therefore, has potentially important implications for patient selection, surgical planning, and outcomes. In this study, enhanced three-dimensional fast spoiled gradient recalled MRI and three-dimensional magnetic resonance angiography with a 3.0-Tesla MRI system were used to detect the anatomic relationship of neural and vascular structures at the trigeminal root entry zone (TREZ) preoperatively. In 27 of 29 patients (93%), surgical findings were consistent with the imaging results. All patients treated with MVD achieved complete pain relief. The usefulness of high-resolution MRI in revealing the neurovascular contact at the TREZ was demonstrated, and it could be used to facilitate the selection of treatment modality. Thus, MVD can be chosen for patients who are most likely to benefit from this intracranial procedure.
微血管减压术(MVD)现已成为治疗三叉神经痛(tic douloureux)的标准疗法。MVD 的目标是从致病血管解压三叉神经根,以期达到永久性治愈,且无或仅有轻微的感觉缺失。因此,术前识别神经血管压迫对患者选择、手术规划和结果具有潜在的重要意义。在这项研究中,使用增强型三维快速扰相梯度回波 MRI 和 3.0T MRI 系统的三维磁共振血管造影术,术前检测三叉神经根入口区(TREZ)的神经和血管结构的解剖关系。在 29 例患者中的 27 例(93%)中,手术结果与影像学结果一致。所有接受 MVD 治疗的患者均完全缓解疼痛。高分辨率 MRI 显示了在 TREZ 处神经血管接触的有用性,它可以用于促进治疗方式的选择。因此,对于最有可能从这种颅内手术中获益的患者,可以选择 MVD。