Griffith Kevin E, Jenkins Eric, Haft Jonathan
Cardiovascular Perfusion Services, University of Michigan Hospitals, Ann Arbor, Michigan 48109-5863, USA.
Perfusion. 2009 May;24(3):169-72. doi: 10.1177/0267659109346663. Epub 2009 Sep 30.
Massive pulmonary embolism (PE) is associated, historically, with a high mortality rate.Treatment options include systemic anticoagulation, catheter-directed thrombolytic therapy, surgical embolectomy, fragmentation techniques, and catheter embolectomy. Extracorporeal membrane oxygenation (ECMO) repeatedly has demonstrated effectiveness in providing cardiopulmonary support for the patient with a massive PE too unstable to undergo thrombolysis or embolectomy. The present case study describes a morbidly obese patient, status post gastric bypass surgery, who presented with PE, and acute respiratory and cardiac failure. A description of the patient's management plan, which includes a simple, rapidly deployed ECMO system (Levitronix CentriMag And Jostra Quadrox D), systemic- and catheter-directed thrombolytic therapy and rheolytic thrombectomy (AngioJet Series 3000, Possis Medical, Minneapolis, MN).
从历史上看,大面积肺栓塞(PE)与高死亡率相关。治疗选择包括全身抗凝、导管定向溶栓治疗、外科栓子切除术、碎裂技术和导管栓子切除术。体外膜肺氧合(ECMO)已多次证明,对于因大面积PE而病情过于不稳定、无法进行溶栓或栓子切除术的患者,它在提供心肺支持方面是有效的。本病例研究描述了一名病态肥胖患者,该患者接受胃旁路手术后出现PE,并伴有急性呼吸和心力衰竭。文中描述了患者的管理计划,其中包括一个简单、快速部署的ECMO系统(Levitronix CentriMag和Jostra Quadrox D)、全身和导管定向溶栓治疗以及流变血栓切除术(AngioJet 3000系列,Possis Medical,明尼阿波利斯,明尼苏达州)。