NOTCH1、FBXW7 突变与 T 系急性淋巴细胞白血病的预后
Mutations of NOTCH1, FBXW7, and prognosis in T-lineage acute lymphoblastic leukemia.
出版信息
Haematologica. 2009 Oct;94(10):1338-40. doi: 10.3324/haematol.2009.012047.
Abstract
From the genetic standpoint, T-lineage acute lymphoblastic leukemia is a heterogeneous disease and comprises a number of different subtypes. In this perspective article, Dr. Mullighan analyzes the relationship between somatic mutations in or and the prognosis of T-lineage acute lymphoblastic leukemia. See related article on page 1383.
摘要
从遗传角度来看，T 细胞系急性淋巴细胞白血病是一种异质性疾病，包含多种不同亚型。在这篇观点文章中， Mullighan 博士分析了 或 中的体细胞突变与 T 细胞系急性淋巴细胞白血病预后之间的关系。详见 1383 页相关文章。
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