Hurley S F, Williams S L, McNeil J J
Cancer Epidemiology Centre, Anti-Cancer Council of Victoria.
Med J Aust. 1990 Mar 5;152(5):259-60, 263-6. doi: 10.5694/j.1326-5377.1990.tb120923.x.
Prescribing of hypotensive agents, beta-blockers and diuretics was analysed using data from the Pharmaceutical Benefits Scheme, adjusted to reflect prescribing for hypertension, over 1977-1987. Prescribing of these three drug groups combined increased by approximately 50% over the period. Notable trends were decreased prescribing of bendrofluazide, chlorothiazide and methyldopa and increased prescribing of hydrochlorothiazide with amiloride, atenolol, metoprolol and prazosin, and, most recently, captopril and enalapril. The increase in prescribing of drugs for hypertension, combined with the choice of more expensive drugs, has resulted in a substantial increase in the drug costs associated with treating hypertension.
利用药品福利计划的数据对降压药、β受体阻滞剂和利尿剂的处方进行了分析，数据经调整以反映1977年至1987年期间高血压的处方情况。在这一时期，这三类药物的联合处方量增加了约50%。显著趋势是苄氟噻嗪、氯噻嗪和甲基多巴的处方量减少，而氢氯噻嗪与阿米洛利、阿替洛尔、美托洛尔和哌唑嗪，以及最近的卡托普利和依那普利的处方量增加。高血压药物处方量的增加，再加上选择了更昂贵的药物，导致治疗高血压的药物成本大幅增加。
