Direct and indirect modulation of neuronal calcium currents by G-protein activation.
作者信息
Dolphin A C, Huston E, Scott R H
机构信息
Department of Pharmacology, St George's Hospital Medical School, London, U.K.
出版信息
Biochem Soc Symp. 1990;56:45-60.
PMID:1979491
Abstract
Evidence is presented for modulation of the various components of neuronal Ca2+ currents by G-proteins and by gamma-aminobutyric acid B (GABAB) receptor activation. The mechanism of these interactions and the possible involvement of second messengers is discussed. The role of inhibition of Ca2+ channels in presynaptic inhibition of neurotransmitter release is examined.
摘要
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