Maimanee Tahia A, Al-Hazmi Safyia
Department of Biology, Collage of Science, Kingdom Abdel Aziz University, P.O. Box: l1853 Jeddah 21463, Saudi Arabia.
J Egypt Soc Parasitol. 2009 Aug;39(2):653-63.
Depression is regarded as one of the widespread psychiatric diseases. Most probably none is free from depression. A number of researches recorded the relationship between acute depression and reduction in the level of cholesterol of depressed people. In this study, blood samples were collected from 144 depressed subjects, some were visiting, and others were residents in the Psychological Health Hospital and King Fahd Hospital in Jeddah. The necessary tests were carried out on these samples in order to know the level of cholesterol. They were categorized into two groups: subjects with acute depression (60 patients), and those with mild depression (84 patients) according to the criteria of the physician and the psychiatrist in the hospital. Data collected from each patient included the social status, financial status and other information. The results showed a close relationship between acute depression and reduction in blood cholesterol (less than 160 mg/dl). This study is compatible with others that confirm the hypothesis declaring the close relationship between acute depression and low blood cholesterol. The results also showed that the youth category was more exposed to acute depression with low level of cholesterol than the other categories. Also, the sex differences did not affect the incidence of depression, as it was comparable in men and women. However, when age and sex were grouped together, men in the age group of 51-60 years were more exposed to acute depression with low level of cholesterol than women. Besides, the social perspective showed that the divorced and the widowed were more likely to have acute depression accompanied with a low level of cholesterol than other social categories.
抑郁症被视为一种广泛传播的精神疾病。很可能没有人能免于抑郁症。许多研究记录了急性抑郁症与抑郁症患者胆固醇水平降低之间的关系。在这项研究中，从144名抑郁症患者身上采集了血样，其中一些是前来就诊的，另一些是吉达心理健康医院和法赫德国王医院的住院患者。对这些样本进行了必要的检测，以了解胆固醇水平。根据医院内科医生和精神科医生的标准，他们被分为两组：急性抑郁症患者（60例）和轻度抑郁症患者（84例）。从每位患者收集的数据包括社会地位、经济状况和其他信息。结果显示急性抑郁症与血液胆固醇降低（低于160毫克/分升）之间存在密切关系。这项研究与其他证实急性抑郁症与低血胆固醇之间密切关系这一假设的研究结果一致。结果还表明，青年组比其他组更容易患急性抑郁症且胆固醇水平较低。此外，性别差异并不影响抑郁症的发病率，因为男性和女性的发病率相当。然而，当按年龄和性别分组时，51至60岁年龄组的男性比女性更容易患急性抑郁症且胆固醇水平较低。此外，从社会角度看，离婚者和丧偶者比其他社会群体更有可能患伴有低胆固醇水平的急性抑郁症。
