Burke Emily L, Walvekar Rohan R, Lin James, Hagan Joseph, Kluka Evelyn A
Department of Otolaryngology and Head Neck Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Int J Pediatr Otorhinolaryngol. 2009 Dec;73(12):1725-8. doi: 10.1016/j.ijporl.2009.09.009. Epub 2009 Sep 30.
To determine the efficacy of common solutions used to dissolve blood clots blocking tympanostomy tubes (TTs) of differing lengths and diameters.
An ex vivo experimental study.
Ear models were built by the study investigator. Tympanostomy tubes were inserted into the models and blocked with blood clots. Test solutions were applied to the blood clots, and time for clearance was recorded via microscopic visual confirmation.
Richards T-tube had higher odds of unclogging than collar button tubes (odds ratio: 2.37, 95% confidence intervals 1.02-5.54, p=0.042). Vinegar and 3% hydrogen peroxide were most effective for Richards T-tubes and collar button tubes, respectively.
Common solutions (vinegar and hydrogen peroxide) were more effective than antibiotic drops in clearing blood clot blocking TTs.
确定用于溶解阻塞不同长度和直径鼓膜造孔管（TTs）的血凝块的常用溶液的疗效。
一项体外实验研究。
由研究人员构建耳部模型。将鼓膜造孔管插入模型并用血凝块阻塞。将测试溶液应用于血凝块，并通过显微镜视觉确认记录清除时间。
理查兹T型管比纽扣式管的疏通几率更高（优势比：2.37，95%置信区间1.02 - 5.54，p = 0.042）。醋和3%过氧化氢分别对理查兹T型管和纽扣式管最有效。
在清除阻塞鼓膜造孔管的血凝块方面，常用溶液（醋和过氧化氢）比抗生素滴耳液更有效。
