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Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays.
Nat Protoc. 2009;4(10):1471-501. doi: 10.1038/nprot.2009.98. Epub 2009 Sep 17.
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Potential application of FoldX force field based protein modeling in zinc finger nucleases design.
Sci China Life Sci. 2011 May;54(5):442-9. doi: 10.1007/s11427-011-4159-9. Epub 2011 Mar 31.
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Simultaneous screening and validation of effective zinc finger nucleases in yeast.
PLoS One. 2013 May 31;8(5):e64687. doi: 10.1371/journal.pone.0064687. Print 2013.
7
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences.
BMC Bioinformatics. 2010 Nov 2;11:543. doi: 10.1186/1471-2105-11-543.
8
Targeted mutagenesis in zebrafish using customized zinc-finger nucleases.
Nat Protoc. 2009;4(12):1855-67. doi: 10.1038/nprot.2009.209.
9
Design and testing of zinc finger nucleases for use in mammalian cells.
Methods Mol Biol. 2008;435:47-61. doi: 10.1007/978-1-59745-232-8_4.
10
High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases.
Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):12028-33. doi: 10.1073/pnas.0914991107. Epub 2010 May 27.

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Machine-guided dual-objective protein engineering for deimmunization and therapeutic functions.
Cell Syst. 2025 Jul 16;16(7):101299. doi: 10.1016/j.cels.2025.101299. Epub 2025 Jun 3.
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C7-Substituted Quinolines as Potent Inhibitors of AdeG Efflux Pumps in .
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Unconstrained Precision Mitochondrial Genome Editing with αDdCBEs.
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Neuroepigenetic Editing.
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Systems for Targeted Silencing of Gene Expression and Their Application in Plants and Animals.
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Corneal gene therapy: Structural and mechanistic understanding.
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Targeted DNA Demethylation: Vectors, Effectors and Perspectives.
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Manipulation of Murine Mitochondrial DNA Heteroplasmy with mtZFNs.
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Stem Cell-Based Therapeutic Approaches in Genetic Diseases.
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Multidimensional control of therapeutic human cell function with synthetic gene circuits.
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本文引用的文献

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DNA-binding Specificity Is a Major Determinant of the Activity and Toxicity of Zinc-finger Nucleases.
Mol Ther. 2008 Feb;16(2):352-358. doi: 10.1038/sj.mt.6300357. Epub 2016 Dec 7.
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High-frequency modification of plant genes using engineered zinc-finger nucleases.
Nature. 2009 May 21;459(7245):442-5. doi: 10.1038/nature07845. Epub 2009 Apr 29.
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Synthesis of programmable integrases.
Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5053-8. doi: 10.1073/pnas.0812502106. Epub 2009 Mar 12.
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Targeted transgene integration in plant cells using designed zinc finger nucleases.
Plant Mol Biol. 2009 Apr;69(6):699-709. doi: 10.1007/s11103-008-9449-7. Epub 2008 Dec 27.
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Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases.
Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19821-6. doi: 10.1073/pnas.0810475105. Epub 2008 Dec 8.
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Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays.
Nucleic Acids Res. 2009 Jan;37(Database issue):D279-83. doi: 10.1093/nar/gkn606. Epub 2008 Sep 23.
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Progress and prospects: zinc-finger nucleases as gene therapy agents.
Gene Ther. 2008 Nov;15(22):1463-8. doi: 10.1038/gt.2008.145. Epub 2008 Sep 11.
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Protein engineering: The fate of fingers.
Nature. 2008 Sep 11;455(7210):160-4. doi: 10.1038/455160a.

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