Hazani Ron, Coots Bradley K, Buntic Rudolf F, Brooks Darrell
Buncke Clinic, Division of Microsurgical Transplantation and Replantation, California Pacific Medical Center, San Francisco, CA 94114, USA.
Ann Plast Surg. 2009 Nov;63(5):496-8. doi: 10.1097/SAP.0b013e3181953a49.
Not all patients seeking autogenous breast reconstruction have sufficient donor tissue for a bilateral reconstruction. Identical twin isotransplantation, as a model system for allotransplantation without immunologic barriers, broadens the definition of "spare parts" surgery. In this case, we demonstrate the simultaneous transplantation of both autogenous and syngeneic deep inferior epigastric perforator flaps for bilateral breast reconstruction. As our understanding of immunology evolves, allotransplantation may further increase our reconstructive options for other postmastectomy patients.
并非所有寻求自体乳房重建的患者都有足够的供区组织进行双侧重建。同卵双胞胎间的同基因移植，作为一种无免疫屏障的同种异体移植模型系统，拓宽了“备用组织”手术的定义。在本病例中，我们展示了同时移植自体和同基因的腹壁下深动脉穿支皮瓣用于双侧乳房重建。随着我们对免疫学认识的不断发展，同种异体移植可能会进一步增加我们为其他乳房切除术后患者提供的重建选择。
