Abdul M A, Shittu S O, Randawa J A, Shehu M S
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital Zaria, Nigeria.
Niger J Clin Pract. 2009 Sep;12(3):289-93.
Cancer of the cervix is the commonest malignancy of the genital tract in Nigeria. In an atmosphere of opportunistic screening due to lack of a national screening programme, studies are needed to determine patients at risk of premalignant lesions of the cervix.
To determine cervical smear pattern in patients with chronic pelvic inflammatory disease and investigate the potential of chronic pelvic inflammatory disease as a risk factor to cervical dysplasia.
Case-control study.
Department of Obstetrics and Gynaecology, Ahmadu Bello University Teaching Hospital Zaria, Nigeria.
Three hundred and sixty-nine premenopausal women attending the gynaecologic and family planning clinics of Ahmadu Bello University Teaching Hospital Zaria, Nigeria from January to December 2000.
Of the 369 women that had cervical cytology by Pap smear, 163 (44%) had chronic pelvic inflammatory disease (cases) while 206 (56%) were non chronic PID patients (control). There was no statistical significance in the mean age between the two groups. The mean age at first coitus and marriage of all the women were 17.92.7 years and 18.5 3.4 years respectively. There were 52 dysplastic smears encountered, giving a prevalence rate of 140/1,000 or 14% for Cervical Intraepithelial Neoplasia. There were higher cases of dysplasia in the chronic PID group than in the control and this differences was statistically significant (p<0.05). Other risk factors to dysplasia identified include high parity (>4) and age of first coitus less than 20 years. Only 10% of all the women screened were aware of both cervical cancer and Pap smear.
Women with chronic pelvic inflammatory disease are probably at higher risk of developing cervical dysplasia than women without chronic pelvic inflammatory disease. Cervical cancer screening programmes should be intensified in chronic pelvic inflammatory disease patients. However, further studies are needed in our setting to verify the association between pelvic inflammatory disease and cervical dysplasia.
宫颈癌是尼日利亚生殖道最常见的恶性肿瘤。由于缺乏全国性筛查计划，在机会性筛查的情况下，需要开展研究以确定有宫颈癌前病变风险的患者。
确定慢性盆腔炎患者的宫颈涂片模式，并调查慢性盆腔炎作为宫颈发育异常危险因素的可能性。
病例对照研究。
尼日利亚扎里亚阿哈迈杜·贝洛大学教学医院妇产科。
2000年1月至12月在尼日利亚扎里亚阿哈迈杜·贝洛大学教学医院妇科和计划生育诊所就诊的369名绝经前妇女。
在369名接受巴氏涂片宫颈细胞学检查的妇女中，163名（44%）患有慢性盆腔炎（病例组），而206名（56%）为非慢性盆腔炎患者（对照组）。两组的平均年龄无统计学差异。所有妇女首次性交和结婚的平均年龄分别为17.9±2.7岁和18.5±3.4岁。共发现52例发育异常涂片，宫颈上皮内瘤变的患病率为140/1000或14%。慢性盆腔炎组的发育异常病例高于对照组，且差异具有统计学意义（p<0.05）。确定的其他发育异常危险因素包括多产（>4次）和首次性交年龄小于20岁。在所有接受筛查的妇女中，只有10%了解宫颈癌和巴氏涂片。
患有慢性盆腔炎的妇女可能比没有慢性盆腔炎的妇女患宫颈发育异常的风险更高。应加强对慢性盆腔炎患者的宫颈癌筛查计划。然而，在我们的研究环境中还需要进一步研究以证实盆腔炎与宫颈发育异常之间的关联。
