Chong H T, Tan C T
Division of Neurology, Department of Medicine, University of Malaya, 50603 Kuala Lumpur, Neurology Laboratory, University Malaya Medical Centre, 59100 Kuala Lumpur, Malaysia.
Med J Malaysia. 2008 Dec;63(5):356-61.
Multiple sclerosis, although a rare disease in Asia, often presents significant diagnostic challenges to clinicians. There has been rapid advancement in the understanding of the underlying genetic influence, pathophysiology, investigation and treatment recently. This paper reviewed the latest development of various aspects of the disease and examined the differences between the manifestations of Asian and Western patients. The implications of these differences to investigation and treatment were also touched upon.
多发性硬化症在亚洲虽是一种罕见疾病,但常常给临床医生带来重大的诊断挑战。最近在对其潜在遗传影响、病理生理学、检查及治疗的认识方面取得了迅速进展。本文回顾了该疾病各方面的最新进展,并探讨了亚洲和西方患者临床表现的差异。还提及了这些差异对检查和治疗的影响。