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植物病原体生物学中的 GO(基因本体论):黄单胞菌基因组会议报告。

Passing GO (gene ontology) in plant pathogen biology: a report from the Xanthomonas Genomics Conference.

机构信息

BIOMERIT Research Centre, Department of Microbiology, BioSciences Institute, University College Cork, Ireland.

出版信息

Cell Microbiol. 2009 Dec;11(12):1689-96. doi: 10.1111/j.1462-5822.2009.01387.x. Epub 2009 Oct 5.

Abstract

In mid-July a workshop entitled the 'Xanthomonas Genomics Conference' took place at the stunning location of Pingree Park, Colorado State University, USA. This meeting, which was supported this time round by United States Department of Agriculture and US National Science Foundation, was the third official workshop dedicated to the study of phytopathogens belonging to the species Xanthomonas. One of the major goals of this meeting was to discuss the insight that comparative analysis of Xanthomonas genomes has given both to an understanding of the ability of this important group of bacteria to exploit an extraordinary diversity of plant hosts and host tissues, and to the development of needed improvements in disease control and prevention. In this report we give an overview of recent developments in this field that were presented during the meeting. These highlights included the unveiling of 11 new Xanthomonas genomic sequences, structural and functional insights into the peptide Ax21 elicitor, the first description of small non-coding RNAs in Xanthomonas and the role they play in the regulation of virulence, as well as a description of novel type III-secreted effectors which target different hosts.

摘要

7 月中旬,在美国科罗拉多州立大学平格里公园举行了一场题为“黄单胞菌基因组学会议”的研讨会。此次会议由美国农业部和美国国家科学基金会共同支持,是第三次专门针对属于黄单胞菌属的植物病原菌进行研究的正式研讨会。此次会议的主要目标之一是讨论比较分析黄单胞菌基因组所带来的启示,这些启示不仅使人们了解了这组重要细菌利用植物宿主和组织多样性的能力,也为疾病控制和预防提供了必要的改进。在本报告中,我们概述了会议期间介绍的该领域的最新进展。这些亮点包括公布了 11 个新的黄单胞菌基因组序列、对肽 Ax21 激发子的结构和功能的深入了解、首次描述了黄单胞菌中的小非编码 RNA 及其在调控毒力中的作用,以及对靶向不同宿主的新型 III 型分泌效应物的描述。

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