Philips Gary T, Carew Thomas J
Department of Neurobiology and Behavior and the Center for the Neurobiology of Learning and Memory, University of California-Irvine, Irvine, CA 92607-4450, USA.
Cell. 2009 Oct 2;139(1):23-5. doi: 10.1016/j.cell.2009.09.020.
In the formation of long-term memories, a "spaced" distribution of study sessions is more beneficial than closely spaced "massed" study sessions. Pagani et al. (2009) examine the molecular basis of this spacing effect in Drosophila and find a role for the SHP2 homolog, corkscrew, an activator of Ras/MAPK signaling, in establishing optimal spacing intervals.
在长期记忆的形成过程中，学习时段的“间隔式”分布比紧密排列的“集中式”学习时段更有益。帕加尼等人（2009年）研究了果蝇中这种间隔效应的分子基础，并发现SHP2同源物“螺旋状”（Ras/MAPK信号的激活剂）在建立最佳间隔时间方面发挥了作用。
