Rekhi Bharat, Karpate Arti, Deodhar Kedar K, Chinoy R F
Department of Pathology, Tata Memorial Hospital, Mumbai, India.
Indian J Pathol Microbiol. 2009 Oct-Dec;52(4):554-8. doi: 10.4103/0377-4929.56165.
Sertoli-Leydig cell tumors (SLCTs) of the ovary with mesenchymal heterologous elements are uncommon. Only few such cases have been documented, showing presence of only mesenchymal heterologous elements at the metastatic site. We report an unusual case in a young girl who presented with an omental mass that was consistent with histopathological features of a high-grade sarcoma, with prominent rhabdomyoblastic differentiation of the embryonal type. The sections from her ovarian mass for which she was operated a year back displayed features of a poorly differentiated SLCT with heterologous elements, including focal rhabdomyoblastic differentiation. This is one of the rare cases, to the best of our knowledge, where only rhabomyosarcomatous elements were identified at the metastatic site, mimicking a primary abdominal rhabdomyosarcoma, in a case of an ovarian SLCT. Further, this case reinforces the presence of rhabdomyosarcomatous elements in an ovarian SLCT to be associated with an aggressive disease course.
伴有间叶性异源成分的卵巢支持-间质细胞瘤（SLCTs）并不常见。仅有少数此类病例被记录在案，显示转移部位仅存在间叶性异源成分。我们报告了一名年轻女孩的罕见病例，她出现了一个大网膜肿块，其组织病理学特征与高级别肉瘤相符，具有显著的胚胎型横纹肌母细胞分化。她一年前接受手术的卵巢肿块切片显示为伴有异源成分的低分化SLCT特征，包括局灶性横纹肌母细胞分化。据我们所知，这是罕见的病例之一，在一例卵巢SLCT中，转移部位仅发现横纹肌肉瘤成分，酷似原发性腹部横纹肌肉瘤。此外，该病例进一步证实卵巢SLCT中存在横纹肌肉瘤成分与侵袭性病程相关。
