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引用本文的文献

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本文引用的文献

1
Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys.胎儿期和婴儿期经产前雄激素化的雌性恒河猴多囊卵巢综合征的内分泌前驱因素
Biol Reprod. 2008 Jul;79(1):154-63. doi: 10.1095/biolreprod.108.067702. Epub 2008 Apr 2.
2
In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development.在人类中,早期皮质醇生物合成提供了一种保障女性性发育的机制。
J Clin Invest. 2006 Apr;116(4):953-60. doi: 10.1172/JCI25091.
3
Absence of the clitoris in a 13-year-old adolescent: medical implications for child and adolescent health.一名13岁青少年阴蒂缺失:对儿童及青少年健康的医学影响
J Pediatr Adolesc Gynecol. 2005 Dec;18(6):415-8. doi: 10.1016/j.jpag.2005.09.011.
4
Female genital appearance: "normality" unfolds.女性生殖器外观:“正常状态”逐渐展现。
BJOG. 2005 May;112(5):643-6. doi: 10.1111/j.1471-0528.2004.00517.x.
5
Biologic data of Macaca mulatta, Macaca fascicularis, and Saimiri sciureus used for research at the Fiocruz primate center.用于菲奥克鲁兹灵长类动物中心研究的恒河猴、食蟹猴和松鼠猴的生物学数据。
Mem Inst Oswaldo Cruz. 2004 Oct;99(6):581-9. Epub 2004 Nov 18.
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Masculinization of female fetus due to use of orally given progestins.
J Am Med Assoc. 1960 Mar 5;172:1028-32. doi: 10.1001/jama.1960.03020100036007.
7
[Hyperandrogenism and pregnancy].[高雄激素血症与妊娠]
Ann Endocrinol (Paris). 2002 Oct;63(5):443-51.
8
Maternal serum androgens in pregnant women with polycystic ovarian syndrome: possible implications in prenatal androgenization.多囊卵巢综合征孕妇的母血雄激素:对产前雄激素化的潜在影响
Hum Reprod. 2002 Oct;17(10):2573-9. doi: 10.1093/humrep/17.10.2573.
9
Uroplakin and androgen receptor expression in the human fetal genital tract: insights into the development of the vagina.人胎儿生殖道中尿路上皮膜蛋白和雄激素受体的表达:对阴道发育的见解
J Urol. 2000 Sep;164(3 Pt 2):1048-51. doi: 10.1097/00005392-200009020-00031.
10
Timing of prenatal androgen exposure: anatomical and endocrine effects on juvenile male and female rhesus monkeys.产前雄激素暴露的时机:对幼年雄性和雌性恒河猴的解剖学和内分泌学影响
Horm Behav. 2000 Aug;38(1):52-66. doi: 10.1006/hbeh.2000.1608.

恒河猴(猕猴属)阴蒂长度的变异

Variation in clitoral length in rhesus macaques (Macaca mulatta).

作者信息

Goldschmidt Beatriz, Cabello Pedro H, Kugelmeier Tatiana, Pereira Barbara B, Lopes Claudia A, Fasano Daniele M, Andrade Marcia C, Santos Joice S, Marinho Antonio M

机构信息

Primatology Department, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

出版信息

J Am Assoc Lab Anim Sci. 2009 Sep;48(5):482-5.

PMID:19807967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2755016/
Abstract

Clitoromegaly in the neonatal period is an important morphologic sign that can be useful for sexual determination in aberrant cases. In rhesus monkeys, differentiation of the external genitalia occurs early during gestation (at 55 to 60 d) and is complete by approximately 80 d. Most of the critical steps in genital differentiation in primates occur prenatally. We sought to determine clitoral size in normal rhesus monkeys (Macaca mulatta) and possible effects of age and inheritance. Clitoral length was highly variable and had no relationship to fertility. Statistical evaluation revealed no association in the distribution of daughters with and without clitoris between mothers with and without clitoris. However, even when mated with several female monkeys, some male macaques produced primarily daughters without clitoris.

摘要

新生儿期阴蒂肥大是一种重要的形态学体征,在异常病例中可用于性别判定。在恒河猴中,外生殖器的分化在妊娠早期(55至60天)发生,并在大约80天时完成。灵长类动物生殖器分化的大多数关键步骤都发生在产前。我们试图确定正常恒河猴(猕猴)的阴蒂大小以及年龄和遗传的可能影响。阴蒂长度变化很大,与生育能力无关。统计评估显示,有阴蒂和无阴蒂的母亲所生女儿的分布没有关联。然而,即使与几只雌猴交配,一些雄猕猴主要生出无阴蒂的女儿。