X连锁视网膜色素变性分子遗传学研究的新策略
New strategies in molecular genetic studies of X-linked retinitis pigmentosa.
作者信息
Jay M, Inglehearn C
机构信息
Department of Clinical Ophthalmology, University of London.
出版信息
Eye (Lond). 1990;4 ( Pt 5):737-42. doi: 10.1038/eye.1990.105.
PMID:1980893
Abstract
New techniques developed in the past few years are being used to isolate the genes responsible for X-linked retinitis pigmentosa. The use of hypervariable probes in linkage, the construction of genetic and physical maps, and the search for putative gene sequences of interest are described.
摘要
过去几年中开发的新技术正被用于分离导致X连锁视网膜色素变性的基因。文中描述了在连锁分析中使用高变探针、构建遗传图谱和物理图谱，以及寻找感兴趣的假定基因序列的情况。
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