X连锁视网膜色素变性分子遗传学研究的新策略
New strategies in molecular genetic studies of X-linked retinitis pigmentosa.
作者信息
Jay M, Inglehearn C
机构信息
Department of Clinical Ophthalmology, University of London.
出版信息
Eye (Lond). 1990;4 ( Pt 5):737-42. doi: 10.1038/eye.1990.105.
PMID:1980893
Abstract
New techniques developed in the past few years are being used to isolate the genes responsible for X-linked retinitis pigmentosa. The use of hypervariable probes in linkage, the construction of genetic and physical maps, and the search for putative gene sequences of interest are described.
摘要
过去几年中开发的新技术正被用于分离导致X连锁视网膜色素变性的基因。文中描述了在连锁分析中使用高变探针、构建遗传图谱和物理图谱，以及寻找感兴趣的假定基因序列的情况。
相似文献
1
New strategies in molecular genetic studies of X-linked retinitis pigmentosa.X连锁视网膜色素变性分子遗传学研究的新策略
Eye (Lond). 1990;4 ( Pt 5):737-42. doi: 10.1038/eye.1990.105.
2
DNA analysis and recombination in X-linked retinitis pigmentosa.
Eye (Lond). 1990;4 ( Pt 1):204-9. doi: 10.1038/eye.1990.27.
3
DNA probes in X-linked retinitis pigmentosa.X连锁视网膜色素变性中的DNA探针
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 4):467-74.
4
Non-allelic mutations in X-linked retinitis pigmentosa.X连锁视网膜色素变性中的非等位基因突变。
Clin Genet. 1989 May;35(5):338-42. doi: 10.1111/j.1399-0004.1989.tb02954.x.
5
[Molecular genetic diagnosis in X chromosome-linked retinitis pigmentosa].[X 染色体连锁视网膜色素变性的分子遗传学诊断]
Klin Monbl Augenheilkd. 1987 Oct;191(4):307-9. doi: 10.1055/s-2008-1050516.
6
Carrier detection in X-linked retinitis pigmentosa by multipoint DNA analysis. Problems due to genetic heterogeneity.通过多点DNA分析进行X连锁视网膜色素变性的携带者检测。遗传异质性导致的问题。
Ophthalmic Paediatr Genet. 1991 Jun;12(2):99-103. doi: 10.3109/13816819109023681.
7
Usher syndrome type I is not linked to D1S81 (pTHH 33): evidence for genetic heterogeneity.
Ann Genet. 1990;33(2):105-8.
8
Carrier detection in X-pigmentary retinal dystrophy (X-linked retinitis pigmentosa) by DNA restriction fragment length polymorphism studies.通过DNA限制性片段长度多态性研究对X连锁性视网膜色素变性（X-连锁视网膜色素变性）进行携带者检测。
Aust N Z J Ophthalmol. 1988 May;16(2):67-74. doi: 10.1111/j.1442-9071.1988.tb01252.x.
9
Genetic counseling in X-linked retinitis pigmentosa.X连锁视网膜色素变性的遗传咨询
J Pediatr Ophthalmol Strabismus. 1989 May-Jun;26(3):140-5. doi: 10.3928/0191-3913-19890501-11.
10
X-linked retinitis pigmentosa: a molecular genetic approach to isolating the defective genes.X连锁视网膜色素变性：分离缺陷基因的分子遗传学方法。
Prog Clin Biol Res. 1989;314:83-97.
引用本文的文献
1
Prenatal exclusion of Norrie's disease.诺里病的产前排除
Br J Ophthalmol. 1992 Aug;76(8):491-3. doi: 10.1136/bjo.76.8.491.
Zotero 插件