Schermerhorn Marc
Section of Endovascular Surgery, Beth Israel Deaconess Medical Center, 110 Francis St, Boston, MA 02215, USA.
JAMA. 2009 Nov 11;302(18):2015-22. doi: 10.1001/jama.2009.1502. Epub 2009 Oct 6.
Ruptured abdominal aortic aneurysm (AAA) is a common cause of death. Abdominal aortic aneurysms tend to be asymptomatic until the time of rupture, which has a mortality rate of greater than 80%. Therefore, elective repair prior to rupture is preferred if life expectancy is reasonable and the risk of rupture outweighs the risk of repair. Mr F, a 66-year-old man with a 5.2-cm AAA, illustrates the issues surrounding monitoring and treating AAA. Risk factors for AAA include older age, male sex, smoking history, and a family history of AAA. Screening for AAA with ultrasound has been shown to prevent rupture, prevent AAA-related death, and be cost-effective. Risk factors for rupture include larger diameter, female sex, and smoking history. Endovascular repair has lower operative mortality and complications and has replaced standard open surgery in more than half of patients. However, long-term survival is similar after endovascular and open surgical repair. Those at risk of AAA who would benefit from repair should undergo screening.
腹主动脉瘤破裂是常见的死亡原因。腹主动脉瘤在破裂前往往没有症状,其破裂后的死亡率超过80%。因此,如果预期寿命合理且破裂风险超过修复风险,首选在破裂前进行择期修复。F先生,一名66岁的男性,患有5.2厘米的腹主动脉瘤,说明了围绕腹主动脉瘤监测和治疗的问题。腹主动脉瘤的危险因素包括老年、男性、吸烟史和腹主动脉瘤家族史。超声筛查腹主动脉瘤已被证明可预防破裂、预防与腹主动脉瘤相关的死亡且具有成本效益。破裂的危险因素包括直径较大、女性和吸烟史。血管内修复的手术死亡率和并发症较低,在超过一半的患者中已取代了标准的开放手术。然而,血管内修复和开放手术修复后的长期生存率相似。那些有腹主动脉瘤风险且能从修复中获益的人应该接受筛查。