Takaha N, Kobayashi Y, Takahara S, Okuyama A, Harada H, Sato B, Yoshida T, Takai S
Department of Urology, Osaka University School of Medicine.
Hinyokika Kiyo. 1990 Nov;36(11):1309-12.
A 41-year-old woman was hospitalized for evaluation of diabetes mellitus and hypertension. The hormonal and radiological examinations revealed that she had pheochromocytoma of bilateral adrenal gland and medullary carcinoma of thyroid gland. Therefore, she was diagnosed as having Sipple's syndrome. She had no definite familial history, but her two sisters, already dead, had been strongly suspected of having had pheochromocytoma. First, bilateral adrenalectomy was performed and secondly, total thyroidectomy, excision of parathyroid and cervical lymph node dissection were performed. Histopathological diagnosis was pheochromocytoma of bilateral adrenal gland, medullary carcinoma of thyroid gland and chief cell hyperplasia of parathyroid gland. We report a case of Sipple's syndrome, which probably is the 88th case in Japan, with the review of the previous Japanese literature.
一名41岁女性因糖尿病和高血压入院评估。激素和影像学检查显示她患有双侧肾上腺嗜铬细胞瘤和甲状腺髓样癌。因此，她被诊断为患有斯-李综合征。她没有明确的家族病史，但她的两个已去世的姐妹曾被高度怀疑患有嗜铬细胞瘤。首先进行了双侧肾上腺切除术，其次进行了甲状腺全切除术、甲状旁腺切除术和颈部淋巴结清扫术。组织病理学诊断为双侧肾上腺嗜铬细胞瘤、甲状腺髓样癌和甲状旁腺主细胞增生。我们报告一例斯-李综合征病例，这可能是日本的第88例，并回顾了以往的日本文献。
