Zhao Jing, Lu Xiong, Wang Jianxin, Weng Jie
Key Laboratory of Advanced Technologies of Materials, Southuwest Jiaotong University, Chengdu 610031, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Aug;26(4):795-8.
In this work, the titanium powder was used for preparing highly interconnected porous scaffolds by impregnating polymer method. Subsequently, the electrochemical method and the biomimetic mineralization method were adopted to deposit calcium phosphate coatings on the sintered scaffold which was supposed to improve the scaffold bioactivity. The experimental results show, with the use of the two methods, the scaffolds are successfully covered by the deposition of the nano-net structure calcium phosphate coating, and they hold their three dimensional interconnected porous structures. Therefore, this kind of bioactive composite scaffold with such mechanical strength as that of woven bone should be a promising bone graft in clinical applications.
在本研究中，采用浸渍聚合物法使用钛粉制备高度互连的多孔支架。随后，采用电化学方法和仿生矿化方法在烧结支架上沉积磷酸钙涂层，以提高支架的生物活性。实验结果表明，使用这两种方法，支架成功地被纳米网状结构的磷酸钙涂层覆盖，并且保持其三维互连的多孔结构。因此，这种具有编织骨机械强度的生物活性复合支架在临床应用中应该是一种有前途的骨移植材料。
