Ruiz-Allec Laura D, Peñaloza-López Yolanda R, Ocaña-Plante Nieves del R, Valdez-González Teresa, López-Star Ellery
Instituto Nacional de Rehabilitación, Servicio de Audiología, México DF, México.
Acta Otorrinolaringol Esp. 2009 Jul-Aug;60(4):253-9. doi: 10.1016/j.otorri.2009.01.002. Epub 2009 Jun 18.
To identify and describe peripheral and central audiological abnormalities of patients with Vogt Koyanagi Harada syndrome.
Prospective, cross-sectional, observational, descriptive study. Vogt Koyanagi Harada patients referred from an ophthalmologic centre were assessed for signs and symptoms of auditory pathology. Peripheral audiological and central auditory processing tests were performed. To standardize the latter, methodological controls were matched for sex, age and audiometric chart.
21 patients were included (3 male, 18 female), mean age 40.7 years (+/-11.82). Nine of the 21 complained of tinnitus and nine suspected hearing loss. Exclusively or mainly sensorial abnormalities of pure tone audiometric chart were documented in 61.9% (mainly selective troughs at 4 and 8 kHz); 95.3% of patients had deficit in high-frequency audiometry. Five of the patients had sensorial disorders in the speech audiometry. No central auditory processing disorder was seen.
Most of the patients with Vogt Koyanagi Harada syndrome had objective peripheral audiological abnormalities, although few revealed any symptoms.
识别并描述小柳原田综合征患者的外周和中枢听觉异常。
前瞻性、横断面、观察性、描述性研究。对眼科中心转诊的小柳原田综合征患者进行听觉病理学体征和症状评估。进行外周听力学和中枢听觉处理测试。为使后者标准化，在性别、年龄和听力图方面进行了方法学对照匹配。
纳入21例患者（3例男性，18例女性），平均年龄40.7岁（±11.82）。21例中有9例主诉耳鸣，9例怀疑听力损失。纯音听力图仅出现或主要出现感觉异常的情况占61.9%（主要是4kHz和8kHz处的选择性低谷）；95.3%的患者高频听力测定存在缺陷。5例患者言语听力测定存在感觉障碍。未发现中枢听觉处理障碍。
大多数小柳原田综合征患者存在客观的外周听力学异常，尽管很少有患者表现出任何症状。
