Damstra T
Environ Health Perspect. 1977 Aug;19:297-307. doi: 10.1289/ehp.7719297.
The pathological effects of lead on the renal, nervous, reproductive, endocrine, and immune systems have been reviewed. Emphasis is placed on reported subclinical effects due to chronic, low-level lead exposure. The crucial issue of whether subtle behavioral, intellectual, and developmental impairment occurs in young children, as a result of lead-induced CNS damage is discussed in detail. This issue remains unresolved. Further studies are needed in order to determine the long-term health effects of continuous, low-level lead exposure.
铅对肾脏、神经、生殖、内分泌和免疫系统的病理影响已得到综述。重点在于因长期低水平铅暴露而报告的亚临床效应。详细讨论了幼儿是否会因铅诱导的中枢神经系统损伤而出现轻微行为、智力和发育障碍这一关键问题。该问题仍未得到解决。需要进一步开展研究,以确定持续低水平铅暴露对健康的长期影响。