• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

小脑浦肯野细胞的树突形成。

Dendrite formation of cerebellar Purkinje cells.

机构信息

Department of Cellular Biophysics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.

出版信息

Neurochem Res. 2009 Dec;34(12):2078-88. doi: 10.1007/s11064-009-0073-y. Epub 2009 Oct 10.

DOI:10.1007/s11064-009-0073-y
PMID:19821027
Abstract

During postnatal cerebellar development, Purkinje cells form the most elaborate dendritic trees among neurons in the brain, which have been of great interest to many investigators. This article overviews various examples of cellular and molecular mechanisms of formation of Purkinje cell dendrites as well as the methodological aspects of investigating those mechanisms.

摘要

在小脑的产后发育过程中,浦肯野细胞形成了大脑中神经元中最精细的树突,这引起了许多研究人员的极大兴趣。本文综述了浦肯野细胞树突形成的各种细胞和分子机制的例子,以及研究这些机制的方法学方面。

相似文献

1
Dendrite formation of cerebellar Purkinje cells.小脑浦肯野细胞的树突形成。
Neurochem Res. 2009 Dec;34(12):2078-88. doi: 10.1007/s11064-009-0073-y. Epub 2009 Oct 10.
2
[Mechanisms for dendritic morphogenesis of cerebellar purkinje cells: role of receptor-type protein tyrosine phosphatase zeta].[小脑浦肯野细胞树突形态发生的机制:受体型蛋白酪氨酸磷酸酶ζ的作用]
Nihon Shinkei Seishin Yakurigaku Zasshi. 2007 Jun;27(3):135-40.
3
Dendritic Self-Avoidance and Morphological Development of Cerebellar Purkinje Cells.树突自回避与小脑浦肯野细胞的形态发育。
Cerebellum. 2018 Dec;17(6):701-708. doi: 10.1007/s12311-018-0984-8.
4
Dendritic morphogenesis of cerebellar Purkinje cells through extension and retraction revealed by long-term tracking of living cells in vitro.通过体外活细胞长期追踪揭示的小脑浦肯野细胞树突形态发生:伸展与回缩
Neuroscience. 2006 Aug 25;141(2):663-674. doi: 10.1016/j.neuroscience.2006.04.044. Epub 2006 May 30.
5
Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.蒲肯野细胞和颗粒细胞表达的兰尼碱受体促进小脑浦肯野细胞的树突分化。
Dev Neurobiol. 2014 Apr;74(4):467-80. doi: 10.1002/dneu.22139. Epub 2013 Nov 4.
6
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons.质膜钙ATP酶2(PMCA2)基因敲除小鼠小脑的分子改变表明浦肯野神经元存在异常。
Mol Cell Neurosci. 2007 Feb;34(2):178-88. doi: 10.1016/j.mcn.2006.10.010. Epub 2006 Dec 5.
7
Atypical protein kinase C regulates primary dendrite specification of cerebellar Purkinje cells by localizing Golgi apparatus.非典型蛋白激酶 C 通过定位高尔基器调节小脑浦肯野细胞的初级树突特化。
J Neurosci. 2010 Dec 15;30(50):16983-92. doi: 10.1523/JNEUROSCI.3352-10.2010.
8
Effects of 1-naphthyl acetyl spermine on dendrite formation by cultured cerebellar Purkinje cells.1-萘乙酰精胺对培养的小脑浦肯野细胞树突形成的影响。
Neurosci Lett. 2009 Oct 2;462(1):30-2. doi: 10.1016/j.neulet.2009.06.068. Epub 2009 Jun 26.
9
Aligned neurite bundles of granule cells regulate orientation of Purkinje cell dendrites by perpendicular contact guidance in two-dimensional and three-dimensional mouse cerebellar cultures.在二维和三维小鼠小脑培养物中,颗粒细胞排列的神经突束通过垂直接触引导来调节浦肯野细胞树突的方向。
J Comp Neurol. 2006 Nov 10;499(2):274-89. doi: 10.1002/cne.21102.
10
The effects of reduced climbing and parallel fibre input on Purkinje cell dendritic growth.
Brain Res. 1976 Jun 4;109(1):133-51. doi: 10.1016/0006-8993(76)90384-x.

引用本文的文献

1
TRPC3 Channel Activity and Viability of Purkinje Neurons can be Regulated by a Local Signalosome.TRPC3通道活性和浦肯野神经元的活力可由一个局部信号体调节。
Front Mol Biosci. 2022 Feb 21;9:818682. doi: 10.3389/fmolb.2022.818682. eCollection 2022.
2
Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TRIM32 缺乏会损害中年小鼠的运动功能和浦肯野细胞。
Front Aging Neurosci. 2021 Aug 6;13:697494. doi: 10.3389/fnagi.2021.697494. eCollection 2021.
3
Gjd2b-mediated gap junctions promote glutamatergic synapse formation and dendritic elaboration in Purkinje neurons.

本文引用的文献

1
Cerebellum and nonmotor function.小脑与非运动功能。
Annu Rev Neurosci. 2009;32:413-34. doi: 10.1146/annurev.neuro.31.060407.125606.
2
Transfer of small interfering RNA by single-cell electroporation in cerebellar cell cultures.小脑细胞培养中单细胞电穿孔介导的小干扰RNA转染
J Neurosci Methods. 2009 Mar 30;178(1):80-6. doi: 10.1016/j.jneumeth.2008.11.025. Epub 2008 Dec 9.
3
SCLIP is crucial for the formation and development of the Purkinje cell dendritic arbor.SCLIP对浦肯野细胞树突状分支的形成和发育至关重要。
Gjd2b 介导的缝隙连接促进浦肯野神经元中谷氨酸能突触的形成和树突的分支。
Elife. 2021 Aug 4;10:e68124. doi: 10.7554/eLife.68124.
4
The Physiological Functions of the Golgin Vesicle Tethering Proteins.高尔基体膜泡拴系蛋白的生理功能
Front Cell Dev Biol. 2019 Jun 18;7:94. doi: 10.3389/fcell.2019.00094. eCollection 2019.
5
Aberrant Development and Synaptic Transmission of Cerebellar Cortex in a VPA Induced Mouse Autism Model.丙戊酸诱导的小鼠自闭症模型中小脑皮质的异常发育和突触传递
Front Cell Neurosci. 2018 Dec 21;12:500. doi: 10.3389/fncel.2018.00500. eCollection 2018.
6
Embryology.胚胎学。
Handb Clin Neurol. 2018;154:29-44. doi: 10.1016/B978-0-444-63956-1.00002-3.
7
Propofol Exposure in Early Life Induced Developmental Impairments in the Mouse Cerebellum.早年接触丙泊酚会导致小鼠小脑发育受损。
Front Cell Neurosci. 2017 Nov 22;11:373. doi: 10.3389/fncel.2017.00373. eCollection 2017.
8
Calcium Signaling, PKC Gamma, IP3R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development.钙信号转导、蛋白激酶 C 同工型 γ、三磷酸肌醇受体 1 和钙激活氯离子通道蛋白 8 连接脊髓小脑共济失调症和浦肯野细胞树突发育
Curr Neuropharmacol. 2018 Jan 30;16(2):151-159. doi: 10.2174/1570159X15666170529104000.
9
Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin.Lhx1/5 通过调节 Espin 控制浦肯野细胞的树突发生和棘突形态发生。
Nat Commun. 2017 May 18;8:15079. doi: 10.1038/ncomms15079.
10
Toll-Like Receptor 4 Deficiency Impairs Motor Coordination.Toll样受体4缺陷会损害运动协调性。
Front Neurosci. 2016 Feb 16;10:33. doi: 10.3389/fnins.2016.00033. eCollection 2016.
J Neurosci. 2008 Jul 16;28(29):7387-98. doi: 10.1523/JNEUROSCI.1942-08.2008.
4
Neurosteroids in the Purkinje cell: biosynthesis, mode of action and functional significance.浦肯野细胞中的神经甾体:生物合成、作用方式及功能意义
Mol Neurobiol. 2008 Apr-Jun;37(2-3):116-25. doi: 10.1007/s12035-008-8024-1. Epub 2008 Jun 3.
5
Space and time-resolved gene expression experiments on cultured mammalian cells by a single-cell electroporation microarray.通过单细胞电穿孔微阵列对培养的哺乳动物细胞进行空间和时间分辨基因表达实验。
N Biotechnol. 2008 Jun;25(1):55-67. doi: 10.1016/j.nbt.2008.03.002. Epub 2008 Apr 18.
6
Phosphorylation of Homer3 by calcium/calmodulin-dependent kinase II regulates a coupling state of its target molecules in Purkinje cells.钙/钙调蛋白依赖性激酶II对Homer3的磷酸化作用调节浦肯野细胞中其靶分子的偶联状态。
J Neurosci. 2008 May 14;28(20):5369-82. doi: 10.1523/JNEUROSCI.4738-07.2008.
7
Progress in transduction of cerebellar Purkinje cells in vivo using viral vectors.使用病毒载体在体内转导小脑浦肯野细胞的研究进展。
Cerebellum. 2008;7(3):273-8. doi: 10.1007/s12311-008-0012-5.
8
Single-cell electroporation of adult sensory neurons for gene screening with RNA interference mechanism.利用RNA干扰机制对成年感觉神经元进行单细胞电穿孔以进行基因筛选。
J Neurosci Methods. 2008 May 30;170(2):204-11. doi: 10.1016/j.jneumeth.2008.01.018. Epub 2008 Jan 31.
9
Mode of action and functional significance of estrogen-inducing dendritic growth, spinogenesis, and synaptogenesis in the developing Purkinje cell.雌激素诱导发育中的浦肯野细胞树突生长、棘突形成和突触形成的作用方式及功能意义。
J Neurosci. 2007 Jul 11;27(28):7408-17. doi: 10.1523/JNEUROSCI.0710-07.2007.
10
The microtubule destabilizer stathmin mediates the development of dendritic arbors in neuronal cells.
J Cell Sci. 2007 Apr 15;120(Pt 8):1447-56. doi: 10.1242/jcs.001461. Epub 2007 Mar 27.