Department of Cellular Biophysics, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.
Neurochem Res. 2009 Dec;34(12):2078-88. doi: 10.1007/s11064-009-0073-y. Epub 2009 Oct 10.
During postnatal cerebellar development, Purkinje cells form the most elaborate dendritic trees among neurons in the brain, which have been of great interest to many investigators. This article overviews various examples of cellular and molecular mechanisms of formation of Purkinje cell dendrites as well as the methodological aspects of investigating those mechanisms.
在小脑的产后发育过程中,浦肯野细胞形成了大脑中神经元中最精细的树突,这引起了许多研究人员的极大兴趣。本文综述了浦肯野细胞树突形成的各种细胞和分子机制的例子,以及研究这些机制的方法学方面。