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动脉瘤样骨囊肿:冷冻手术作为局部辅助治疗的作用。

Aneurysmal bone cyst: the role of cryosurgery as local adjuvant treatment.

机构信息

Department of Orthopaedic Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands.

出版信息

J Surg Oncol. 2009 Dec 15;100(8):719-24. doi: 10.1002/jso.21410.

Abstract

BACKGROUND

Aneurysmal bone cysts (ABCs) are most often treated with intralesional surgery (curettage) and additional bone grafting. There is debate on whether or not to use adjuvant therapy to decrease the local recurrence rate. This study is done to assess the outcome of curettage and cryosurgery as a treatment of ABC.

METHODS

We analyzed 80 consecutive cases of ABC treated with curettage and cryosurgery. Patients were followed minimal 24 months after surgery (average 55 months, range 24-122 months) with physical examination and radiographs. Functional outcome was evaluated using the musculoskeletal tumor society score (MSTS).

RESULTS

The 80 patients were all treated with curettage and cryosurgery. Additional bone grafting was used in 73 patients, osteosynthesis in 12 and spondylodesis in 1 patient. Four local recurrences were found in this study, a recurrence rate of 5%. All local recurrences were treated successfully with curettage and cryosurgery again 7-33 months after the initial surgery. Postoperative one fracture, one wound infection, and three transient nerve palsy occurred. The average MSTS score was 29.2 at follow-up.

CONCLUSIONS

The use of cryosurgery as adjuvant therapy results in a lower local recurrence rate when compared to other publications for the treatment of ABC and excellent functional results.

摘要

背景

动脉瘤样骨囊肿(ABC)通常采用病灶内手术(刮除术)和额外植骨治疗。对于是否使用辅助治疗来降低局部复发率存在争议。本研究旨在评估刮除术联合冷冻疗法治疗 ABC 的疗效。

方法

我们分析了 80 例连续的 ABC 患者,均采用刮除术联合冷冻疗法治疗。术后至少随访 24 个月(平均 55 个月,范围 24-122 个月),包括体格检查和影像学检查。采用肌肉骨骼肿瘤学会评分(MSTS)评估功能结果。

结果

80 例患者均接受了刮除术联合冷冻疗法治疗。73 例患者采用了额外植骨,12 例患者采用了内固定,1 例患者采用了脊柱融合术。本研究中发现 4 例局部复发,复发率为 5%。所有局部复发患者均在初次手术后 7-33 个月再次接受了刮除术联合冷冻疗法治疗,均成功治愈。术后发生 1 例骨折、1 例伤口感染和 3 例短暂性神经麻痹。随访时平均 MSTS 评分为 29.2。

结论

与其他 ABC 治疗文献相比,冷冻疗法作为辅助治疗可降低局部复发率,并获得良好的功能结果。

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