Weiner Justin B, Haddad Elias V, Raj Satish R
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Pacing Clin Electrophysiol. 2010 Apr;33(4):e39-42. doi: 10.1111/j.1540-8159.2009.02589.x. Epub 2009 Oct 10.
Brugada syndrome is a genetic disorder associated with an increased risk of sudden cardiac death that has typical electrocardiographic (ECG) patterns. Recently, there have been reports of Brugada ECG patterns seen in critically ill patients who received propofol,(1) and this pattern was associated with a very high imminent mortality. We report a case in which a critically ill patient developed a Brugada ECG pattern following high-dose propofol infusion. Once the ECG pattern was recognized, the propofol was discontinued and the ECG pattern resolved, and the patient was discharged home with no arrhythmic sequelae.
Brugada综合征是一种与心脏性猝死风险增加相关的遗传性疾病,具有典型的心电图(ECG)模式。最近,有报告称在接受丙泊酚治疗的重症患者中出现了Brugada心电图模式,(1) 且这种模式与极高的近期死亡率相关。我们报告一例重症患者在大剂量输注丙泊酚后出现Brugada心电图模式的病例。一旦识别出心电图模式,即停用丙泊酚,心电图模式恢复正常,患者出院时无心律失常后遗症。